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Table 1 Resource utilization

From: Dexmedetomidine versus standard care sedation with propofol or midazolam in intensive care: an economic evaluation

1a. Time to extubation, hours P value
Mean (SD) Median (IQR)
Dexmedetomidine Standard care Dexmedetomidine Standard care
Pooled 166.1 (219.5) 195.1 (220.6) 89.0 (46.0-188.0) 118.0 (53.0-231.0) 0.0003
MIDEX 183.8 (226.4) 214.9 (229.3) 95.0 (59.0-212.0) 143.0 (75.0-232.0) 0.0013
PRODEX 148.3 (211.3) 175.1 (210.0) 69.0 (39.0-164.0) 91.0 (44.0-231.0) 0.0405
1b. Duration of mechanical ventilation, hours P value
Mean (SD) Median (IQR)
Dexmedetomidine Standard care Dexmedetomidine Standard care
Pooled 192.7 (241.1) 213.2 (229.1) 103.0 (51.0-215.0) 139.0 (70.0-265.0) 0.0052
MIDEX 199.2 (237.5) 231.4 (239.9) 115.0 (66.0-216.0) 146.5 (84.0-260.0) 0.0047
PRODEX 186.3 (245.0) 194.7 (216.7) 94.0 (45.0-211.0) 114.0 (47.0-266.0) 0.2049
1c. Duration of actual ICU stay, hours P value
Mean (SD) Median (IQR)
Dexmedetomidine Standard care Dexmedetomidine Standard care
Pooled 271.3 (267.2) 296.0 (265.6) 166.5 (98.5-315.0) 196.0 (116.0-361.0) 0.0210
MIDEX 281.8 (265.0) 318.4 (265.8) 179.5 (115.0-341.0) 217.0 (126.0-365.0) 0.0131
PRODEX 260.8 (269.6) 273.3 (265.0) 146.0 (94.0-293.0) 169.0 (93.0-355.0) 0.4057
1d. Cumulative sum of TISS points P value
Mean (SD) Median (IQR)
Dexmedetomidine Standard care Dexmedetomidine Standard care
Pooled 360 (375) 403 (360) 239 (152-426) 279 (177-503) 0.0030
MIDEX 353 (328) 419 (372) 239 (157-428) 300 (181-507) 0.0094
PRODEX 368 (419) 386 (347) 242 (139-421) 273 (170-501) 0.1064
  1. Duration of ventilator use (1a-b), intensive care unit (ICU) stay (1c), and cumulative sum of Therapeutic Intervention Scoring System (TISS) points (1d) are derived from MIDEX and PRODEX for the economic analysis. In MIDEX, the standard care sedative was midazolam; in PRODEX, it was propofol. IQR, interquartile range (first to third); SD, standard deviation.