|
Variable
|
Metoclopramide group
|
Domperidone group
|
Control group
|
P
value
|
|---|
|
(
n
= 100)
|
(
n
= 99)
|
(
n
= 99)
|
|---|
|
Age (years)
| | | | |
|
Average
|
62.1 ± 18.6
|
65.2 ± 15.1
|
61.3 ± 17.4
|
0.233
|
|
Median
|
64
|
69
|
64
| |
|
Range
|
18 to 93
|
27 to 95
|
20 to 96
| |
|
Male
|
67 (67.0)
|
58 (58.6)
|
72 (72.7)
|
0.107
|
|
Primary diagnosis
| | | | |
|
Respiratory
|
20 (20.0)
|
18 (18.2)
|
22 (22.2)
|
0.777
|
|
Cardiovascular
|
5 (5.0)
|
10 (10.1)
|
9 (9.1)
|
0.375
|
|
Neurological
|
48 (48.0)
|
41 (41.4)
|
39 (39.4)
|
0.439
|
|
Sepsis
|
14 (14.0)
|
11 (11.1)
|
13 (13.1)
|
0.822
|
|
Multitrauma
|
7 (7.0)
|
6 (6.1)
|
10 (10.1)
|
0.537
|
|
Other
|
6 (6.0)
|
13 (13.1)
|
6 (6.1)
|
0.114
|
|
Use of sedatives
|
31 (31.0)
|
30 (30.3)
|
29 (29.3)
|
0.966
|
|
Use of analgesics
|
10 (10.0)
|
12 (12.1)
|
9 (9.1)
|
0.773
|
|
Use of vasopressors
|
24 (24.0)
|
21 (21.2)
|
25 (25.3)
|
0.790
|
|
Ventilation
|
72 (72.0)
|
66 (66.7)
|
68 (68.7)
|
0.713
|
|
Average APACHE II score
|
21.7 ± 7.5
|
20.7 ± 6.6
|
21.0 ± 7.3
|
0.582
|
|
< 20
|
45 (45.0)
|
43 (43.4)
|
43 (43.4)
|
0.967
|
|
≥ 20
|
55 (55.0)
|
56 (56.6)
|
56 (56.6)
| |
|
Average SOFA score
|
9.9 ± 2.9
|
9.7 ± 2.8
|
9.7 ± 2.9
|
0.858
|
|
< 12
|
66 (66.0)
|
68 (68.7)
|
66 (66.7)
|
0.916
|
|
≥ 12
|
34 (34.0)
|
31 (31.3)
|
33 (33.3)
| |
- Data presented as mean ± standard deviation, interquartile range or n (%). APACHE, Acute Physiology and Chronic Health Evaluation; SOFA, Sequential Organ Failure Assessment.
