Metoclopramide or domperidone improves post-pyloric placement of spiral nasojejunal tubes in critically ill patients: a prospective, multicenter, open-label, randomized, controlled clinical trial

Table 1 Patients’ baseline characteristics

Variable	Metoclopramide group	Domperidone group	Control group	P value
Variable	( n = 100)	( n = 99)	( n = 99)	P value
Age (years)
Average	62.1 ± 18.6	65.2 ± 15.1	61.3 ± 17.4	0.233
Median	64	69	64
Range	18 to 93	27 to 95	20 to 96
Male	67 (67.0)	58 (58.6)	72 (72.7)	0.107
Primary diagnosis
Respiratory	20 (20.0)	18 (18.2)	22 (22.2)	0.777
Cardiovascular	5 (5.0)	10 (10.1)	9 (9.1)	0.375
Neurological	48 (48.0)	41 (41.4)	39 (39.4)	0.439
Sepsis	14 (14.0)	11 (11.1)	13 (13.1)	0.822
Multitrauma	7 (7.0)	6 (6.1)	10 (10.1)	0.537
Other	6 (6.0)	13 (13.1)	6 (6.1)	0.114
Use of sedatives	31 (31.0)	30 (30.3)	29 (29.3)	0.966
Use of analgesics	10 (10.0)	12 (12.1)	9 (9.1)	0.773
Use of vasopressors	24 (24.0)	21 (21.2)	25 (25.3)	0.790
Ventilation	72 (72.0)	66 (66.7)	68 (68.7)	0.713
Average APACHE II score	21.7 ± 7.5	20.7 ± 6.6	21.0 ± 7.3	0.582
< 20	45 (45.0)	43 (43.4)	43 (43.4)	0.967
≥ 20	55 (55.0)	56 (56.6)	56 (56.6)
Average SOFA score	9.9 ± 2.9	9.7 ± 2.8	9.7 ± 2.9	0.858
< 12	66 (66.0)	68 (68.7)	66 (66.7)	0.916
≥ 12	34 (34.0)	31 (31.3)	33 (33.3)

Data presented as mean ± standard deviation, interquartile range or n (%). APACHE, Acute Physiology and Chronic Health Evaluation; SOFA, Sequential Organ Failure Assessment.

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