Figure 3

Selenium administration reduces monocyte adhesion to the endothelium under flow conditions. Addition of selenium on human umbilical vein endothelial cells (HUVECs) diminished microparticles-induced monocyte-endothelial interaction (crosshatched bars) after stimulation with microparticles from resuscitated patients under venous flow (left and middle), as well as firm adherence under arterial flow (right) conditions in dynamic adhesion assay, compared with unblocked stimulation with microparticles from resuscitated patients (black bars) and to microparticle-free supernatant from resuscitated patients (dark gray bars). (**P <0.001; *P <0.01).