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Figure 1 | Critical Care

Figure 1

From: Selenium prevents microparticle-induced endothelial inflammation in patients after cardiopulmonary resuscitation

Figure 1

Microparticles from resuscitated patients enhance monocyte-endothelial interaction under flow conditions. Stimulation of human umbilical vein endothelial cells (HUVECs) with microparticles from resuscitated patients (black bars) leads to enhanced monocyte-endothelial interaction under venous flow (left and middle), and firm adherence under arterial flow (right) conditions in the dynamic adhesion assay, compared to microparticle-free supernatant from resuscitated patients (dark gray bars) and stimulation with microparticles from healthy subjects (light gray bars): ***P <0.0001; **P <0.001; # P <0.05; ns = not statistically significant). CPR, cardiopulmonary resuscitation; ICAM-1, intracellular adhesion molecule-1; VCAM-1, vascular cell adhesion molecule-1.

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