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Table 5 Diagnostic accuracy of Angus and colleagues’ criteria for detecting community-acquired severe sepsis events, stratified by infection category [1 ]

From: Discharge diagnoses versus medical record review in the identification of community-acquired sepsis

Diagnostic property Lung ( n = 166) Kidney ( n = 59) Abdominal ( n = 73) Skin ( n = 49) Other ( n = 32) Overall ( n = 379)
Sensitivity (%) 41.0 (28.6 to 54.3) 43.5 (23.2 to 65.5) 36.8 (16.3 to 61.6) 42.9 (9.9 to 81.6) 58.3 (27.7 to 84.8) 42.6 (33.7 to 51.9)
Specificity (%) 83.8 (75.3 to 90.3) 77.8 (60.8 to 89.9) 88.9 (77.4 to 95.8) 90.5 (77.4 to 97.3) 90.0 (68.3 to 98.8) 85.6 (80.7 to 88.7)
Positive predictive value (%) 59.5 (43.3 to 74.4) 55.6 (30.8 to 78.5) 53.8 (25.1 to 80.8) 42.9 (9.9 to 81.6) 77.8 (40.0 to 97.2) 58.4 (47.5 to 68.8)
Negative predictive value (%) 71.0 (62.1 to 78.8) 68.3 (51.9 to 81.9) 80.0 (67.7 to 89.2) 90.5 (77.4 to 97.3) 78.3 (56.3 to 92.5) 75.9 (70.5 to 80.7)
Likelihood ratio positive 2.5 (1.5 to 4.3) 2.0 (0.9 to 4.2) 3.3 (1.3 to 8.6) 4.5 (1.3 to 15.9) 5.8 (1.4 to 23.6) 3.0 (2.1 to 4.3)
Likelihood ratio negative 0.70 (0.56 to 0.88) 0.73 (0.49 to 1.08) 0.71 (0.50 to 1.01) 0.63 (0.33 to 1.21) 0.46 (0.23 to 0.92) 0.67 (0.57 to 0.79)
Area under ROC curve 0.62 (0.55 to 0.70) 0.61 (0.48 to 0.73) 0.63 (0.51 to 0.75) 0.67 (0.46 to 0.87) 0.74 (0.58 to 0.90) 0.64 (0.59 to 0.69)
  1. Data presented as mean (95% confidence interval). ROC, receiver operating characteristics.