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Table 3 Baseline characteristics and hospital course of community-acquired sepsis events (identified by manual chart review) and sepsis events identified by Martin and colleagues’ discharge diagnoses

From: Discharge diagnoses versus medical record review in the identification of community-acquired sepsis

Characteristic Community-acquired sepsis (column %) ( n = 156) Martin-sepsis (column%) ( n = 55) Discordances favoring community-acquired sepsis (column %) ( n = 113) Discordances favoring Martin-sepsis (column %) ( n = 12) Pvalue Community-acquired versus Martin-sepsis discordancesa
Mean age (SD) 69.7 (9.1) 70.6 (8.8) 69.3 (9.3) 70.3 (10.3) 0.72
Sex      
 Male 58.3 67.3 54.9 66.7 0.43
 Female 41.7 32.7 45.1 33.3  
Race      
 White 64.7 58.2 68.1 33.3 0.92
 Black 35.3 41.8 31.9 66.7  
Income      
  < $20,000 25.6 27.3 25.7 33.3 0.70
 $20,000 to 34,000 37.2 41.8 34.5 33.3
 $35,000 to 74,000 21.8 21.8 21.2 16.7
  ≥ $75,000 9.6 1.8 12.4 0.0
 Unknown 5.8 7.3 6.2 16.7
Education      
 Less than high school 22.4 21.8 21.2 8.3 0.70
 High school graduate 31.4 30.9 32.7 41.7
 Some college 28.2 27.3 29.2 33.3
 College or higher 18.0 20.0 16.7 16.7
Health behaviors      
 Tobacco use      
  Never 32.3 34.6 32.1 41.7 0.79
  Past 52.3 52.7 50.9 41.7
  Current 15.5 12.7 17.0 16.7
 Alcohol use      
  None 67.7 67.3 69.6 83.3 0.36
  Moderate 29.0 29.1 27.7 16.7
  Heavy 3.2 3.6 2.7 0.0
Chronic medical conditions      
 Atrial fibrillation 15.6 17.3 17.8 50.0 0.03
 Cancer 19.5 22.2 19.0 27.3 0.53
 Chronic kidney disease 26.9 27.3 25.7 16.7 0.48
 Chronic lung disease 18.0 7.3 22.1 8.3 0.22
 Coronary artery disease 29.6 24.5 33.3 41.7 0.57
 Deep vein thrombosis 12.9 16.4 11.6 16.7 0.62
 Diabetes 35.3 47.3 34.5 83.3 <0.001
 Dyslipidemia 66.7 70.0 64.2 55.6 0.61
 Hypertension 70.3 35.5 71.4 58.3 0.36
 Myocardial infarction 18.3 20.8 18.8 33.3 0.26
 Obesity (abnormal BMI or WC) 62.8 63.6 61.1 50.0 0.46
 Peripheral artery disease 3.9 5.5 3.54 8.33 0.47
 Stroke 19.4 25.5 18.8 41.7 0.09
Infection type      
 Lung 51.3 29.1 57.5 8.3 <0.001
 Kidney 17.3 27.3 13.3 25.0  
 Abdominal 14.7 3.6 19.5 8.3  
 Skin 6.4 10.9 5.3 16.7  
 Other 10.3 29.1 4.4 41.7  
28-hour SOFA score 2 (1 to 3) 2 (1 to 3) 1 (0 to 3) 2 (1 to 3) 0.56
Median (IQR) MEDS score 9 (6 to 13) 11 (6 to 13) 9 (6 to 11) 9 (6 to 10.5) 0.12
Admission to ICU 13.5 23.6 8.0 8.3 0.96
Hospital mortality 10.3 25.5 5.3 33.3 0.006
  1. BMI, body mass index; IQR, interquartile range; MEDS, Mortality in Emergency Department Sepsis; SD, standard deviation; SOFA, Sequential Organ Failure Assessment; WC, waist circumference. aThe prevalence of each subject characteristic was evaluated by comparing the discordant pairs for each sepsis definition.