Table 4 Impact of ventilator mode and level of assistance on patient-ventilator interaction and asynchrony indices

Inspiratory trigger delay (msec)

 level₅₀

162 (109–241)

157 (138–289)

185 (140–305)

 level₁₀₀

170 (140–282)

124 (100–238)

224 (176–280)^£

 level₁₅₀

266 (140–427)

164 (99–278)*

201 (166–317)

Expiratory trigger delay (msec)

 level₅₀

156 (112–191)

151 (125–175)

152 (107–175)

 level₁₀₀

212 (176–273)

157 (140–188)*

182 (116–230)

 level₁₅₀

255 (227–541)

146 (131–218)*

225 (169–333)

Relationship between P_max and EAdi_max (r²)

 level₅₀

0.02 (0.01-0.04)

0.56 (0.51-0.65)*

0.02 (0.00-0.04)^£

 level₁₀₀

0.03 (0.01-0.08)

0.85 (0.78-0.90)*

0.04 (0.00-0.07)^£

 level₁₅₀

0.03 (0.01-0.06)

0.64 (0.43-0.88)*

0.03 (0.02-0.08)^£

Relationship between V_T and EAdi_AUC (r²)

 level₅₀

0.15 (0.14-0.19)

0.48 (0.40-0.57)*

0.39 (0.25-0.45)*

 level₁₀₀

0.13 (0.06-0.22)

0.64 (0.60-0.79)*

0.29 (0.21-0.42)

 level₁₅₀

0.02 (0.01-0.06)

0.72 (0.65-0.88)*

0.28 (0.25-0.41)*

Ineffective efforts (n.min⁻¹)

 level₅₀

0.00 (0.00-0.07)

0.00 (0.00-0.00)*

0.00 (0.00-0.00)*

 level₁₀₀

0.03 (0.00-0.26)

0.00 (0.00-0.00)*

0.00 (0.00-0.00)*

 level₁₅₀

0.27 (0.01-1.23)

0.00 (0.00-0.00)*

0.00 (0.00-0.00)*

Auto-triggering (n.min⁻¹)

 level₅₀

0.00 (0.00-0.03)

0.00 (0.00-0.00)

0.00 (0.00-0.00)

 level₁₀₀

0.00 (0.00-0.03)

0.00 (0.00-0.00)

0.00 (0.00-0.00)

 level₁₅₀

0.00 (0.00-0.00)

0.00 (0.00-0.00)

0.00 (0.00-0.00)

Double triggering (n.min⁻¹)

 level₅₀

0.00 (0.00-0.00)

0.42 (0.08-0.50)*

0.00 (0.00-0.00)^£

 level₁₀₀

0.00 (0.00-0.18)

0.33 (0.10-0.92)*

0.00 (0.00-0.10)^£

 level₁₅₀

0.00 (0.00-0.21)

0.30 (0.02-0.87)*

0.00 (0.00-0.20)^£

Asynchrony index (%)

 level₅₀

0.21 (0.00-0.65)

1.41 (0.34-2.91)*

0.13 (0.00-0.44)^£

 level₁₀₀

0.61 (0.04-1.28)

1.73 (0.38-2.69)

0.00 (0.00-0.58)^£

 level₁₅₀

1.65 (0.58-5.77)

1.17 (0.05-3.99)

0.19 (0.00-1.12)