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Table 1 Comparison of baseline characteristics between patients treated with and without erythropoietin at admission

From: Erythropoietin improves long-term neurological outcome in acute ischemic stroke patients: a randomized, prospective, placebo-controlled clinical trial

Variable

Group 1 ( n = 71)

Group 2 ( n = 71)

Pvaluea

Age (years)

65.6 ± 11.3

64.1 ± 11.4

0.481

Male

64.8% (46)

69.0% (49)

0.593

Hypertension

71.8% (51)

63.4% (45)

0.282

Diabetes mellitus

31% (22)

36.6% (26)

0.478

Current smoking

25.4% (18)

33.8% (24)

0.270

Previous stroke by history

19.7% (14)

23.9% (17)

0.542

Previous stroke by brain MRI

56.3% (40)

63.4% (45)

0.392

Obstructive CADb

12.7% (9)

19.7% (14)

0.255

Old myocardial infarction

7.0% (5)

9.9% (7)

0.546

RBC count (× 106/ml)

4.68 ± 0.69

4.72 ± 0.69

0.743

Hemoglobin (g/dl)

14.0 ± 1.9

14.1 ± 1.8

0.876

WBC count (× 103/ml)

7.72 ± 2.35

7.81 ± 2.48

0.821

Total cholesterol level

189.1 ± 40.1

190.2 ± 36.4

0.864

HDL (mg/dl)

50.3 ± 18.1

45.6 ± 10.9

0.062

LDL (mg/dl)

114.0 ± 35.4

118.8 ± 31.9

0.415

Creatinine (mg/dl)

1.02 ± 0.41

1.01 ± 0.38

0.916

BMI (kg/m2)

23.9 ± 3.8

24.9 ± 3.3

0.086

HbA1C

6.88 ± 1.83

6.75 ± 1.92

0.699

SBP (mmHg)

143 ± 21

145 ± 23

0.669

DBP (mmHg)

80 ± 29

83 ± 12

0.098

Carotid artery stenosisc

15.3% (11)

23.9% (17)

0.192

Statin therapy

45.8% (33)

43.7% (31)

0.794

ACEI/ARB therapy

34.7% (25)

38% (27)

0.681

  1. Data are expressed as mean ± standard deviation or percentage (number) of patients. Group 1, without erythropoietin treatment; Group 2, with erythropoietin treatment. ACEI/ARB, angiotensin-converting enzyme inhibitor/angiotensin II type I receptor blocker; BMI, body mass index; CAD, coronary artery disease (defined as >50% stenosis of epicardial vessel by angiographic finding); DBP, diastolic blood pressure; HbA1C, hemoglobin A1C; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MRI, magnetic resonance imaging; RBC, red blood cell; SBP, systolic blood pressure; WBC, white blood cell. aBy t test or chi-square test. bDefined as the coronary obstruction >50% at least one epicardial vessel. cDefined as common carotid artery or internal carotid artery stenosis >50%.