Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children: a cochrane systematic review and meta-analysis

Rose, Louise; Schultz, Marcus J; Cardwell, Chris R; Jouvet, Philippe; McAuley, Danny F; Blackwood, Bronagh

doi:10.1186/s13054-015-0755-6

Critical Care

Table 1 Characteristics of included studies

From: Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children: a cochrane systematic review and meta-analysis

Study	Patients	System	Comparator	Weaning success
Agarwal, 2013 [29]	48 adults	ASV	Protocolized: VCV to PSV	Not defined
Aghadavoudi, 2012 [20]	81 adults	ASV	Protocolized:	Not defined
Aghadavoudi, 2012 [20]	81 adults	ASV	SIMV (VC) + PS to CPAP	Not defined
Burns, 2013 [30]	92 adults	Smartcare/PS	Protocolized: PSV	Not defined although outcomes reported for first and successful extubation
Davis, 1989 [21]	40 adults	MMV	Protocolized: IMV to CPAP	Not defined
Dongelmans, 2009 [19]	128 adults	ASV	Protocolized: PCV to PSV	Tracheal extubation
Hendrix, 2006 [22]	20 adults	Automode	Protocolized: PRVC to PSV	Not defined
Jouvet, 2013 [14]	30 children	Smartcare/PS	Usual care: PSV	No further need for ventilation for 48 hours after extubation
Kirakli, 2011 [15]	97 adults	ASV	Protocolized:	No further need for ventilation for 48 hours after extubation or with a tracheostomy cannula at day 28
Kirakli, 2011 [15]	97 adults	ASV	AC (VC) to PSV
Lellouche, 2006 [23]	147 adults	Smartcare/PS	Protocolized: PSV or T-piece	Time from inclusion until successful extubation (followed by 72 hours without ventilator support)
Liu, 2013 [31]	39 adults	Smartcare/PS	Protocolized: daily 30 min SBT of CPAP or PSV	48 hours without reintubation after extubation
Petter, 2003 [32]	34 adults	ASV	Protocolized: SIMV to PSV	Not defined
Ramet, 2002 [28]	18 children	Automode	Protocolized: PRVC to VS	Not defined
Rose, 2008 [16]	102 adults	Smartcare/PS	Usual care: PSV	No further need for ventilation for 48 hours after extubation
Roth, 2001 [24]	40 adults	Automode	Protocolized: SIMV to PSV	Not defined
Schädler, 2012 [17]	300 adults	Smartcare/PS	Protocolized: PSV	Not defined though outcomes reported for first and successful extubation
Stahl, 2009 [33]	60 adults	Smartcare/PS	Usual care: PSV	Measured reintubation frequency within 48 hours of extubation
Strickland, 1993 [25]	17 adults	Non-commercial system	Usual care: SIMV to PSV/CPAP	Not defined
Sulzer, 2001 [34]	36 adults	ASV	Protocolized: SIMV to PSV	Not defined
Taniguchi, 2009 [26]	106 adults	MRV	Protocolized: PCV to PSV	Not defined
Walkey [27]	33 adults	Smartcare/PS	Usual care: A/C to PSV	No further need for ventilation for 48 hours after extubation
Xirouchaki, 2008 [18]	208 adults	PAV+	Protocolized: PSV	Not defined

ASV, adaptive support ventilation; CPAP, continuous positive airway pressure; IMV, intermittent mandatory ventilation; MRV, minute respiratory volume; PAV+, proportional assist ventilation; PRVC, pressure regulated volume control; PSV, pressure support ventilation; SBT, spontaneous breathing trial; SIMV, synchronized intermittent mandatory ventilation; VS, volume support.

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