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Table 1 Characteristics of included studies

From: Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children: a cochrane systematic review and meta-analysis

Study Patients System Comparator Weaning success
Agarwal, 2013 [29] 48 adults ASV Protocolized: VCV to PSV Not defined
Aghadavoudi, 2012 [20] 81 adults ASV Protocolized: Not defined
SIMV (VC) + PS to CPAP
Burns, 2013 [30] 92 adults Smartcare/PS Protocolized: PSV Not defined although outcomes reported for first and successful extubation
Davis, 1989 [21] 40 adults MMV Protocolized: IMV to CPAP Not defined
Dongelmans, 2009 [19] 128 adults ASV Protocolized: PCV to PSV Tracheal extubation
Hendrix, 2006 [22] 20 adults Automode Protocolized: PRVC to PSV Not defined
Jouvet, 2013 [14] 30 children Smartcare/PS Usual care: PSV No further need for ventilation for 48 hours after extubation
Kirakli, 2011 [15] 97 adults ASV Protocolized: No further need for ventilation for 48 hours after extubation or with a tracheostomy cannula at day 28
AC (VC) to PSV
Lellouche, 2006 [23] 147 adults Smartcare/PS Protocolized: PSV or T-piece Time from inclusion until successful extubation (followed by 72 hours without ventilator support)
Liu, 2013 [31] 39 adults Smartcare/PS Protocolized: daily 30 min SBT of CPAP or PSV 48 hours without reintubation after extubation
Petter, 2003 [32] 34 adults ASV Protocolized: SIMV to PSV Not defined
Ramet, 2002 [28] 18 children Automode Protocolized: PRVC to VS Not defined
Rose, 2008 [16] 102 adults Smartcare/PS Usual care: PSV No further need for ventilation for 48 hours after extubation
Roth, 2001 [24] 40 adults Automode Protocolized: SIMV to PSV Not defined
Schädler, 2012 [17] 300 adults Smartcare/PS Protocolized: PSV Not defined though outcomes reported for first and successful extubation
Stahl, 2009 [33] 60 adults Smartcare/PS Usual care: PSV Measured reintubation frequency within 48 hours of extubation
Strickland, 1993 [25] 17 adults Non-commercial system Usual care: SIMV to PSV/CPAP Not defined
Sulzer, 2001 [34] 36 adults ASV Protocolized: SIMV to PSV Not defined
Taniguchi, 2009 [26] 106 adults MRV Protocolized: PCV to PSV Not defined
Walkey [27] 33 adults Smartcare/PS Usual care: A/C to PSV No further need for ventilation for 48 hours after extubation
Xirouchaki, 2008 [18] 208 adults PAV+ Protocolized: PSV Not defined
  1. ASV, adaptive support ventilation; CPAP, continuous positive airway pressure; IMV, intermittent mandatory ventilation; MRV, minute respiratory volume; PAV+, proportional assist ventilation; PRVC, pressure regulated volume control; PSV, pressure support ventilation; SBT, spontaneous breathing trial; SIMV, synchronized intermittent mandatory ventilation; VS, volume support.