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Figure 4 | Critical Care

Figure 4

From: Local hemostasis, immunothrombosis, and systemic disseminated intravascular coagulation in trauma and traumatic shock

Figure 4

The inhibition of the activation of fibrinolysis by tranexamic acid revealed microvascular thrombosis and thromboemboli formation in the large vessels in a dog model of hemorrhagic shock. (A) A section of a branch of the portal vein almost completely filled by a mixed thrombus consisting of platelets and fibrin threads in bundles. (B) A section from lung vessels with thrombotic masses consisting of both platelets and fibrin thread. Phosphotungstic acid hematoxylin staining. Adapted with permission from Leandoer and Bergentz [91].

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