Figure 4From: Local hemostasis, immunothrombosis, and systemic disseminated intravascular coagulation in trauma and traumatic shock The inhibition of the activation of fibrinolysis by tranexamic acid revealed microvascular thrombosis and thromboemboli formation in the large vessels in a dog model of hemorrhagic shock. (A) A section of a branch of the portal vein almost completely filled by a mixed thrombus consisting of platelets and fibrin threads in bundles. (B) A section from lung vessels with thrombotic masses consisting of both platelets and fibrin thread. Phosphotungstic acid hematoxylin staining. Adapted with permission from Leandoer and Bergentz [91].Back to article page