Preload dependence indices to titrate volume expansion during septic shock: a randomized controlled trial

Table 2 Hemodynamic characteristics at inclusion

	Control	Preload dependence	P
	(n = 30)	(n = 30)	P
Mean arterial pressure (mm Hg)	68 [64-75]	72 [68-82]	0.08
Central venous pressure (mm Hg)	9 [7-14]	10 [8-12]	0.67
Cardiac index (L.min^-1.m^-2)	3.5 [2.7-4.7]	3.6 [2.9-4.8]	0.43
Hemoglobin (g.dL^-1)	9.8 [8.9-11.6]	10.6 [9.5-11.4]	0.57
Oxygen arterial transport (mL.min^-1.m^-2)	414 [352-619]	468 [395-648]	0.14
ScvO₂ (%)	77 [74-83]	77 [72-84]	0.89
ScvO₂ < 70%	5 (17%)	6 (20%)	1
Extravascular lung water index (mL.kg^-1 PBW)	13 [10-16]	12 [10-16]	0.65
Lactate (mmol.L^-1)	2.7 [2.2-3.6]	2.9 [2.5-5.7]	0.32
Lactate above upper normal laboratory limit	22 (73%)	25 (83%)	0.53
Inotrope treatment	5 (17%)	6 (20%)	1
Vasopressor dose (μg.kg^-1.min^-1)	0.51 [0.26-1.05]	0.60 [0.34-1.14]	0.38

Data are median [interquartile range] or number of patients (%). ScvO₂, superior vena cava oxygenation saturation; PBW, predicted body weight.

ISSN: 1364-8535