Model | Data | Sensitivity : Specificity | α | β | PPV : NPV | ACC | AUROC |
---|---|---|---|---|---|---|---|
Septic shock vs. ICU controls | Metabolomics | 0.92 : 1.0 | 0 | 0.08 | 1.0 : 0.87 | 0.95 | 0.99 ± 0.01 |
Cytokines/chemokines | 0.94 : 0.90 | 0.1 | 0.06 | 0.94 : 0.90 | 0.93 | 0.99 ± 0.01 | |
Combined | 0.94 : 1.0 | 0 | 0.06 | 1.0 : 0.91 | 0.96 | 1.0 | |
APACHE | 0.82 : 0.42 | 0.58 | 0.18 | 0.71 : 0.57 | 0.67 | 0.74 ± 0.07 | |
SOFA | 0.85 : 0.25 | 0.75 | 0.15 | 0.66 : 0.50 | 0.63 | 0.64 ± 0.07 | |
Nonsurvivors vs. survivors | Combined | 1.0 : 0.88 | 0.13 | 0 | 0.89 : 1.0 | 0.94 | 1.0 |
APACHE | 0.63 : 0.75 | 0.25 | 0.38 | 0.71 : 0.67 | 0.69 | 0.78 ± 0.12 | |
SOFA | 0.75 : 0.63 | 0.38 | 0.25 | 0.67 : 0.71 | 0.69 | 0.81 ± 0.11 |