Furosemide | Ethacrynic acid | P | |
---|---|---|---|
Number of patients | 38 | 36 | - |
Demographic | |||
Age (days) | 104 (180) | 135 (181) | 0.57 |
Weight (kg) | 4.6 (3.9) | 4.2 (3.1) | 0.63 |
Body surface area (m2) | 0.27 (0.16) | 0.25 (0.11) | 0.46 |
Correction/palliation | 11/38 (27%) | 10/36 (28%) | 0.96 |
Neonates | 18/38 (45%) | 17/36 (47%) | 0.99 |
Aristotle score | 9.5 (2.5) | 9.7 (2.5) | 0.53 |
CPB (min) | 187 (70) | 204 (102) | 0.43 |
OFF pump (n) | 5/38 (12.5%) | 2/36 (6%) | 0.26 |
XClamp (minutes) | 102 (56) | 100 (75) | 0.88 |
OFF XClamp (n) | 4/33 (12%) | 2/34 (6%) | 0.67 |
DHCA (n) | 7/29 (24%) | 7/32 (22%) | 0.83 |
Baseline (PCICU admission) | |||
Heart rate (beats/min) | 162 (20) | 154 (32) | 0.25 |
Syst art press (mm Hg) | 77 (13) | 81 (19) | 0.35 |
LAP (mm Hg) | 6.9 (2.6) | 7.5 (1.9) | 0.41 |
CVP (mm Hg) | 9.5 (2.9) | 9.5 (2.8) | 0.98 |
CI (L/min/m2) | 2.5 (0.5) | 2.8 (0.8) | 0.19 |
VIS | 22 (18) | 21 (11) | 0.76 |
Cerebral NIRS (%) | 54 (18) | 57 (16) | 0.50 |
Renal NIRS (%) | 68 (20) | 69 (19) | 0.88 |
sCr (mg/dl) | 0.58 (0.20) | 0.57 (0.17) | 0.78 |
CysC (mg/dl) | 1.08 (0.4) | 1.16 (0.3) | 0.58 |
NGAL (pg/ml) | 89 (57) | 93 (69) | 0.78 |
pH | 7.45 (0.1) | 7.45 (0.08) | 0.78 |
HCO3− (M) | 25 (3.6) | 26 (2.5) | 0.55 |
BE | 1.29 (4.8) | 1.88 (3.3) | 0.57 |
Lactates (mM) | 5.6 (3.9) | 6.3 (3.2) | 0.46 |
SaO2 (%) | 92 (11) | 88 (18) | 0.27 |
SvO2 (%) | 60 (21) | 57 (16) | 0.47 |
PaO2/FIO2 | 192 (149) | 141 (124) | 0.15 |