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Table 1 Results of model fitting for five ARDS patients

From: Evaluation of lung recruitment maneuvers in acute respiratory distress syndrome using computer simulation

  

Patient A

Patient B

Patient C

Patient D

Patient E

Parameters obtained from data

Hb (g dl−1)

10.5

10.8

11.5

9.8

9

CO (l min−1)

11.1

7.2

5.6

7.7

5.9

FIO2

0.8

0.9

0.5

0.8

1

Parameters obtained through optimization

VR (b min−1)

12.25

12.14

16.04

17.68

17.0

IE

0.28

0.25

0.38

0.38

0.43

RQ

0.6

0.6

0.9

0.7

0.61

VO2 (ml min−1)

294.3

300

200

257.2

246.8

 

% of compartments collapsed

26

29

12

20

21

Parameters fixed for RM trials

Pv (cm H2O)

15

15

15

15

15

PEEP (cm H2O)

5

5

5

5

5

  

Data

Model

Data

Model

Data

Model

Data

Model

Data

Model

Results of fitting the model to the data

PvO2 (mmHg)

47.3

49.5

38.3

39.4

48

45.4

42.83

42.2

34.5

30.3

PvCO2 (mmHg)

44.4

46.2

55.5

54.4

47.6

49.9

51

48.8

33.82

36.07

Qs/Qt (%)

28.6

31.8

31.7

33.9

22.6

19.4

32.3

31.4

43.1

39.14

PaO2 (mmHg)

153.7

149.9

85.5

87.9

130.5

129.6

110.3

109.6

64.5

64.95

  1. ARDS, acute respiratory distress syndrome; Hb, hemoglobin; CO, cardiac output; FIO2, fraction of inspired oxygen; VR, ventilation rate; IE, inspiratory to expiratory ratio; RQ, respiratory quotient; VO2, oxygen consumption; Pv, ventilator pressure; PEEP, positive end-expiratory pressure; PvO2, partial pressure of oxygen in venous blood; PvCO2, partial pressure of carbon dioxide in venous blood; Qs/Qt, shunt fraction; PaO2, partial pressure of oxygen in arterial blood.