Variable | C. difficile - YES (n = 204) | C. difficile - NO (n = 204) | P value |
---|---|---|---|
Age | 68.6 ± 15 | 68.5 ± 15 | 0.949 |
Gender (% male) | 55% (113) | 57% (116) | 0.765 |
ICU type | 0.770 | ||
Cardiac/Cardiothoracic | 51% (104) | 51% (103) | |
Medical | 43% (88) | 45% (92) | |
Surgical | 6% (12) | 4% (9) | |
Classification of primary diagnosis | 1.00 | ||
Cardiovascular | 24% (49) | 24% (49) | |
Infection | 23% (46) | 23% (46) | |
Gastrointestinal | 14% (28) | 14% (28) | |
Respiratory | 12% (25) | 12% (25) | |
Neurologic | 9% (18) | 9% (18) | |
Cancer | 6% (13) | 6% (13) | |
Trauma | 5% (10) | 5% (10) | |
Renal | 2% (5) | 2% (5) | |
Venous thromboembolism | 1% (3) | 1% (3) | |
Miscellaneous | 3% (7) | 3% (7) | |
SOFA | 6 (0 – 17) | 6 (0 – 18) | 0.798 |
Mechanical ventilation | 74% (151) | 71% (145) | 0.506 |
Immunosuppression | 28% (56) | 32% (65) | 0.329 |
Long PPI exposure (2 or more days) | 83% (170) | 73% (149) | 0.012 |
PPI duration (days) | 7 (0 – 56) | 6 (0 – 96) | 0.488 |
H2RA use | 32% (65) | 36% (73) | 0.403 |
Long H2RA exposure (2 or more days) | 26% (53) | 31% (63) | 0.272 |
H2RA duration (days) | 0 (0 – 21) | 0 (0 – 62) | 0.474 |
Antibiotic use | 94% (191) | 87% (177) | 0.020 |
Total number of antibiotics received | 3 (0 – 7) | 2 (0 – 8) | 0.001 |
Study duration (days) | 9.7 (2.4 – 55.7) | 10 (2 – 99) | 0.253 |