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Table 1 Patient characteristics

From: High-flow nasal cannula oxygen versus non-invasive ventilation in patients with acute hypoxaemic respiratory failure undergoing flexible bronchoscopy - a prospective randomised trial

 

NIV

HFNC

P value

Total number of patients

20

20

 

Gender

   

 Male

13 (65%)

11 (55%)

0.52

 Female

7 (35%)

9 (45%)

Age (years)

68 ± 11

64 ± 12

0.28

SAPS II score

46 ± 10

43 ± 13

0.39

Thrombocytopenia (<50 Mrd/L)

3 (15%)

5 (25%)

0.43

Immunosuppression

8 (40%)

5 (25%)

0.31

Use of vasopressors

10 (50%)

10 (50%)

1.00

Antibiotic therapy

17 (85%)

19 (95%)

0.29

Antimycotic therapy

5 (25%)

6 (30%)

0.72

Antiviral therapy

3 (15%)

7 (35%)

0.14

Main diagnosis

   

 Haematological disorder

4 (20%)

7 (35%)

0.29

 Sepsis

4 (20%)

3 (15%)

0.68

 Lung cancer

2 (10%)

3 (15%)

0.63

 Extrapulmonary solid cancer

2 (10%)

3 (15%)

0.63

 Liver cirrhosis

1 (5%)

1 (5%)

1.00

 Trauma

1 (5%)

1 (5%)

1.00

 Interstitial lung disease

1 (5%)

1 (5%)

1.00

 Alveolar haemorrhage

1 (5%)

0

0.31

 Community-acquired pneumonia

1 (5%)

0

0.31

 Chronic obstructive pulmonary disease

1 (5%)

0

0.31

 Pulmonary arterial hypertension

1 (5%)

0

0.31

 Acquired immunodeficiency syndrome

0

1 (5%)

0.31

 Ileum perforation

1 (5%)

0

0.31

Indication for bronchoscopy

   

 Hospital-acquired pneumonia

10 (50%)

14 (70%)

0.50

 Community-acquired pneumonia

5 (25%)

3 (15%)

 Suspected retention of secretions

3 (15%)

2 (10%)

 Suspected interstitial lung disease

1 (5%)

0

 Suspected alveolar haemorrhage

1 (5%)

0

 Suspected malignancy

0

1 (5%)

Therapy at baseline

   

 Low-flow oxygen via nasal cannula

5 (25%)

2 (10%)

0.23

 Low-flow oxygen via face mask

1 (5%)

3 (15%)

 HFNC

9 (45%)

13 (65%)

 NIV

5 (25%)

2 (10%)

Physiological parameters at baseline

   

 Heart rate (beats/min)

95 ± 14

101 ± 15

0.27

 Mean arterial pressure (mm Hg)

85 ± 11

82 ± 14

0.56

 Respiratory rate (breaths/min)

30 ± 8

30 ± 9

0.86

 PaO2/FiO2 (mm Hg)

163 ± 64

138 ± 69

0.25

 PaCO2 (mm Hg)

43 ± 13

34 ± 6

0.01

 pH

7.43 ± 0.11

7.46 ± 0.07

0.21

  1. Values are given as mean and standard deviation or as numbers and percentages. FiO2, fraction of inspired oxygen; HFNC, high-flow nasal cannula; NIV, non-invasive ventilation; PaCO2, partial pressure of carbon dioxide in arterial blood; PaO2, partial pressure of oxygen in arterial blood; SAPS II, simplified acute physiology score II.