Assessment of ACLF-by-hyponatremia interaction | Estimate of the independent effect of ACLF and hyponatremia | ||||
---|---|---|---|---|---|
Parameter | Hazard ratio (95% CI)* | P value | Parameter | Hazard ratio (95% CI)* | P value |
ACLF at study enrolment | 3.99 (2.92-5.44) | <0.001 | ACLF at study enrolment | 3.78 (2.90-4.93) | <0.0001 |
Hyponatremia at study enrolment | 2.00 (1.33-3.02) | 0.001 | Hyponatremia at study enrolment | 1.81 (1.33-2.47) | 0.0002 |
Combination of independent effects: | |||||
Interaction ACLF-by-hyponatremia | 0.83 (0.47-1.48) | 0.5300 | ACLF/hyponatremia vs. no ACLF/no hyponatremia | 6.85 (3.85-12.19) | <0.0001 |