From: Physiological changes after fluid bolus therapy in sepsis: a systematic review of contemporary data
First author | Journal | Year | Aims of study | Location | Institution(s) | Study type | Population size |
---|---|---|---|---|---|---|---|
Bihari [36] | Shock | 2013 | Investigation of the use and effects of fluid boluses in septic patients following primary resuscitation | Australia | Single centre, academic ICU | Prospective observational study | 50 patients with severe sepsis or septic shock |
Castellanos-Ortega [37] | Critical Care Medicine | 2010 | Evaluation of the impact of a standardised EGDT response to sepsis | Spain | Single centre, academic ICU | Quasi-experimental study | 480 patients with septic shock |
De Backer [38] | New England Journal of Medicine | 2010 | Assessing the effect of noradrenaline as first-line vasopressor on mortality | Europe | 8 centres, mixed ICUs | Randomised clinical trial | 1,679 patients with shock requiring vaspressor therapy. 1,044 patients with sepsis |
Dong [39] | World Journal of Emergency Medicine | 2012 | Investigating the relationship between stroke volume index and passive leg raising and fluid responsiveness | China | 2 centres, general ICUs | Prospective observational study | 32 mechanically ventilated patients with septic shock |
Freitas [40] | British Journal of Anaesthesia | 2013 | Evaluation of the predictive value of automated PPV for fluid responsiveness in patients with sepsis and low tidal volumes | Brazil | Single centre, academic ICU | Prospective observational study | 40 patients with low tidal volume ventilation and severe sepsis or septic shock requiring a fluid challenge |
Gaieski [41] | Critical Care Medicine | 2010 | Evaluation of the impact of a standardised EGDT response to sepsis on time to antibiotic administration and survival | USA | Single centre, academic ICU | Retrospective observational study | 261 patients with severe sepsis and septic shock undergoing EGDT |
Hamzaoui [42] | Critical Care | 2010 | Evaluation of the cardiac consequences of early administration of noradrenaline | France | Single centre, academic ICU | Prospective observational study | 105 patients with septic shock requiring vasopressor commencement following initial fluid resuscitation |
Hanzelka [43] | Supportive Care in Cancer | 2013 | Evaluation of the impact of a standardised EGDT response to sepsis | USA | Single centre, academic ED | Retrospective observational study | 200 patients with cancer and severe sepsis or septic shock presenting to ED |
Jacob [44] | Critical Care Medicine | 2012 | Evaluation of the impact of early monitored sepsis management | Uganda | 2 centres, medical/treatment centres | Prospective observational study | 671 patients with severe sepsis presenting within office hours |
Khwannimit [45] | European Journal of Anaesthesiology | 2012 | Comparing SVV by Vigileo with PPV by monitor to predict fluid responsiveness | Thailand | Single centre, academic ICU | Prospective observational study | 42 patients with septic shock who were mechanically ventilated with tidal volumes >8Â ml/kg requiring fluid resuscitation |
Lakhal [46] | Intensive Care Medicine | 2013 | Identification of fluid responsiveness from IABP and NIBP | France | 3 centres, academic ICU | Prospective observational study | 130 patients with circulatory failure requiring a fluid challenge. 58 patients with septic shock |
Lanspa [47] | Journal of Critical Care | 2012 | Assessment of CVP and shock index to predict haemodynamic response to volume expansion when compared with CVP alone | USA | Single centre, academic ICU | Prospective observational study | 25 patients with septic shock over 14Â years of age |
Machare-Delgado [48] | Journal of Intensive Care Medicine | 2011 | Predicting fluid responsiveness by comparing SVV and inferior vena caval respiratory variation by ECHO during mechanical ventilation | USA | Single centre, medical academic ICU | Prospective observational study | 25 mechanically ventilated vasopressor-dependent patients who required a fluid challenge. 22 patients with severe sepsis or septic shock |
MacRedmond [49] | Quality and Safety in Health Care | 2010 | Evaluation of the impact of implementing a quality initiative on the management of severe sepsis and septic shock | Canada | Single centre, ICU | Quasi-experimental study | 74 patients with severe sepsis or septic shock admitted via ED |
Mahjoub [50] | Intensive Care Medicine | 2012 | Assessment of the impact of volume expansion on patients with left ventricular dysfunction | France | Single centre, academic ICU | Prospective observational study | 83 mechanically ventilated patients with sepsis-induced circulatory failure |
McIntyre [51] | Journal of Critical Care | 2012 | Feasibility study comparing the effects of 5% albumin versus 0.9% saline for resuscitation in septic shock | Canada | 6 centres, academic ED and ICU | Randomised clinical trial | 50 patients with refractory hypotension and sepsis |
Monnet [52] | Critical Care | 2010 | Comparing haemodynamic changes induced by noradrenaline and volume expansion using Vigileo and PiCCO | France | Single centre, academic medical ICU | Prospective observational study | 80 patients with sepsis-induced circulatory failure |
Monnet [53] | Critical Care Medicine | 2011 | Assessing the effects of noradrenaline on haemodynamics in sepsis | France | Single centre, academic medical ICU | Prospective observational study | 25 patients with sepsis-induced fluid-responsive acute circulatory failure with DBP <40Â mmHg, or requiring noradrenaline |
Monnet [54] | Critical Care Medicine | 2013 | Comparing ScvO2 and markers of anaerobic metabolism as predictors of unfavourable changes in oxygen extraction | France | Single centre, academic medical ICU | Prospective observational study | 51 patients with acute circulatory failure undergoing transpulmonary thermodilution monitoring, 40 patients with septic shock |
Monnet [55] | Critical Care Medicine | 2011 | Investigation of the utility of pulse pressure as a surrogate for changes in cardiac output | France | Single centre, academic medical ICU | Prospective observational study | 373 patients with acute circulatory failure requiring a fluid challenge or the introduction or dose increase of noradrenaline. 338 patients with septic shock |
O’Neill [56] | Journal of Emergency Medicine | 2012 | Evaluation of the most difficult elements of a SSC protocol to implement in a community-based ED | USA | Single centre, community ED | Retrospective observational study | 79 with severe sepsis or septic shock remaining hypotensive following 2,000 ml of fluid resuscitation |
Ospina-Tascon [57] | Intensive Care Medicine | 2010 | Evaluation of the effects of fluid administration on microcirculatory alterations in sepsis | Belgium | Single centre, academic ICU | Prospective observational study | 60 patients with severe sepsis requiring fluid challenge. 37 within 24Â hours of diagnosis, 23 after 48Â hours |
Patel [58] | Annals of Pharmacotherapy | 2010 | Investigation of the implementation and effects of introducing the SSC guidelines | USA | Single centre, community ICU | Prospective observational study | 112 patients with sepsis or septic shock |
Pierrakos [59] | Intensive Care Medicine | 2012 | Evaluation of the correlation between changes in MAP and CI following fluid challenge | Belgium | Single centre, academic ICU | Prospective observational study | 51 patients with septic shock undergoing invasive haemodynamic monitoring and requiring a fluid challenge |
Pottecher [60] | Intensive Care Medicine | 2010 | Assessment of sublingual microcirculatory changes in response to fluid challenge | France | 2 centres, academic ED | Prospective observational study | 25 mechanically ventilated patients with severe sepsis or septic shock within 24Â hours of ICU admission demonstrating pre-load dependency |
Sanchez [61] | Anaesthesia and Intensive Care | 2011 | Measuring the response to a fluid load in patients with and without septic shock | Spain | Single centre, academic ICU | Prospective observational study | 32 patients requiring invasive monitoring. 18 patients with septic shock |
Schnell [62] | Critical Care Medicine | 2013 | Assessment of the effects of a fluid challenge on Doppler-based renal resistive index in critically ill patients | France | 3 centres, academic ICUs | Prospective observational study | 35 mechanically ventilated patients with real-time cardiac monitoring requiring a fluid challenge. 30 patients with sepsis |
Sturgess [63] | Anaesthesia and Intensive Care | 2010 | Comparison of aortic corrected flow time, BNP and CVP as predictors of fluid responsiveness | Australia | Single centre, private ICU | Prospective observational study | 10 patients with septic shock requiring a fluid challenge |
Trof [64] | Critical Care Medicine | 2012 | Comparison of volume-guided and pressure-guided hemodynamic management in shocked patients | Netherlands | 2 centres, academic, ICU | Randomised clinical trial | 120 patients with shock requiring invasive haemodynamic monitoring and >48Â hours of ICU admission. 72 patients with sepsis |
van Haren [65] | Shock | 2012 | Evaluation of the effects of hypertonic versus isotonic fluid administration in patients with septic shock | Netherlands | Single centre, academic ICU | Randomised clinical trial | 24 patients with septic shock enrolled within 24Â hours of admission |
Wacharasint [66] | Journal of the Medical Association of Thailand | 2012 | Evaluation of the effectiveness of three dynamic measures of fluid responsiveness in septic shock patients | Thailand | Single centre, medical ICU | Prospective observational study | 20 patients with sepsis and acute circulatory failure with invasive haemodynamic monitoring stable for 15Â minutes prior to inclusion |
Yu [67] | Shock | 2011 | Evaluation of the effects of blood volume analysis compared with pulmonary artery catheter monitoring | North America | Single centre, academic ICU | Randomised clinical trial | 100 patients requiring resuscitation for shock. 69 patients with severe sepsis or septic shock |
Zhang [68] | Journal of Critical Care | 2012 | Investigation of the association between plasma protein levels and subsequent pulmonary oedema | China | Single centre, academic ICU | Retrospective observational study | 62 patients with sepsis undergoing transpulmonary thermodilution assessment requiring fluid |