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Table 4 Risk factors for VAP occurrence before day 28 (univariate and multivariate analyses)

From: Effect of a fever control protocol-based strategy on ventilator-associated pneumonia in severely brain-injured patients

Parameters

Univariate analysis

Multivariate analysis

 

HR

95% CI (HR)

P -value

HR

95% CI (HR)

P -value

Age

0.97

(0.95, 0.98)

<0.001

0.97

(0.95, 0.98)

<0.001

Gender (male)

1.82

(0.88, 3.78)

0.110

   

BMI

0.99

(0.93, 1.05)

0.730

   

Smoking

1.89

(1.09, 3.30)

0.024

1.67

(0.95, 2.93)

0.078

Alcohol intake

0.85

(0.35, 2.09)

0.730

   

Lung contusion

2.41

(1.37, 4.24)

0.002

   

GCS

0.97

(0.85, 1.12)

0.710

   

SAPS II

0.98

(0.95, 1.00)

0.068

1.01

(0.98, 1.04)

0.590

NMB agents

2.11

(0.97, 4.61)

0.061

   

Mannitol

1.25

(0.72, 2.17)

0.430

   

Thiopental

1.36

(0.78, 2.38)

0.270

0.95

(0.53, 1.69)

0.950

Fever control

3.06

(1.58, 5.94)

<0.001

2.73

(1.38, 5.38)

0.005

  1. BMI: body mass index; GCS: Glasgow Coma Scale; NMB: neuromuscular blocker; SAPS II: Simplified Acute Physiology Score II; VAP: ventilator-associated pneumonia.
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Critical Care

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