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Table 4 Outcomes of new-onset atrial fibrillation in patients with sepsis, severe sepsis or septic shock

From: Incidence, risk factors and outcomes of new-onset atrial fibrillation in patients with sepsis: a systematic review

Reference Outcome Patients with new-onset AF (number of patients with outcome/total) Patients without new-onset AF (number of patients with outcome/total) Crude OR P value Adjusted OR P value
Christian et al., 2008 [17] ICU mortality 11/16 (69%) 102/256 (40%) 3.32 (1.12- 9.84) 0.03   
Meierhenrich et al., 2010 [20] ICU mortality 10/23 (44%) 6/27 (22%) 2.69 (0.79-9.17) 0.14   
28-day mortality 9/23 (39%) 6/27 (22%) 2.25 (0.66-7.73) 0.22
Salman et al., 2008 [21] ICU mortality 12/25 (48%) 15/56 (27%) 2.52 (0.95-6.74) 0.06   
In-hospital mortality 16/25 (65%) 20/56 (38%) 3.20 (1.20-8.55) 0.02
28-day mortality 18/25 (72%) 21/56 (38%) 4.29 (1.53-11.97) 0.004 3.28 (1.13-9.57)a 0.03
Walkey et al., 2011 [24] In-hospital mortality 1629/2896 (56%) 13652/36200 (38%) 2.12 (1.97-2.29) <.0001 1.07 (1.04-1.11)b,c n/a
In-hospital ischemic stroke 75/2896 (3%) 249/36200 (1%) 3.84 (2.96-4.98) <.0001 2.70 (2.05-3.57)d n/a
Wells et al., 2011 [26] ICU/in-hospital mortality 95/132 (72%) 189/333 (57%) 1.96 (1.26-3.03) 0.002   
  1. Data are expressed as absolute numbers (%) unless other specified. aAdjusted for the severity of illness at ICU admission measure by the Acute Physiology and Chronic Health Evaluation (APACHE) III predicted mortality rate; badjusted for: age, sex, race/ethnicity, history of diabetes mellitus, hypertension, obesity, heart failure, stroke, myocardial infarction, chronic obstructive pulmonary disease, metastatic or hematologic malignancy, number of organ failures, presence of electrolyte disturbance, source of sepsis, type of organ failure, type of pathogenic organism and use of pulmonary artery catheter; crelative risk; dadjusted for: age, sex, race/ethnicity, history of diabetes mellitus, hypertension, obesity, heart failure, stroke, myocardial infarction, chronic obstructive pulmonary disease, metastatic or hematologic malignancy, number of organ failures, presence of electrolyte disturbance, source of sepsis, type of organ failure, type of pathogenic organism and use of pulmonary artery catheter. AF: atrial fibrillation; ICU: intensive care unit; n/a: not available; OR: odds ratio.