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Table 1 Overview of included studies

From: Incidence, risk factors and outcomes of new-onset atrial fibrillation in patients with sepsis: a systematic review

Reference Setting Number of patients with sepsis/total a Detection method AF Outcome Methodological quality b
Arora et al., 2007 [16] Single center, mixed ICU, Australia. 18/61 Prospective bedside detection +12-lead confirmation n/a Moderate
Christian et al., 2008 [17] Single center, mixed ICU, USA. 274/274 Retrospective review of monitor data from a database developed for benchmarking Death Moderate
Gomez et al., 2012 [18] Multicenter, mixed ICUs, Columbia. 100/100 Prospective detection using telemetry n/a Low
Goodman et al., 2007 [19] Single center, mixed ICU, Israel. 149/611 Prospective bedside detection +12-lead confirmation. n/a Moderate
Meierhenrich et al., 2010 [20] Single center, surgical ICU, Germany. 50/629 Prospective bedside detection +12-lead confirmation Death Moderate
Salman et al., 2008 [21] Single center, mixed ICU, USA. 81/81 Retrospective review of monitor data from a hospital record database Death Moderate
Seguin et al., 2006 [22] Single center, trauma ICU, France. 36/293 Prospective bedside detection +12-lead confirmation n/a Low
Seguin et al., 2004 [23] Single center, surgical ICU, France. 107/460 Prospective bedside detection +12-lead confirmation n/a Moderate
Walkey et al., 2011 [24] Multicenter, acute care hospital, USA. 49,082/49,082 Retrospective review from an administrative claims database using ICD-9-CM codes for detection of AF Death Moderate
Stroke
Walkey et al., 2013 [25]c Multicenter, Medicare hospital, USA. 40,740/40,740d Retrospective review from an administrative claims database using ICD-9-CM codes for detection of AF n/a Moderate
Wells et al., 2011 [26] Single center, medical ICU, USA. 465/1466 Retrospective review from an administrative database, detection of AF using telemetry Death Low
  1. aWhen studies differentiate between sepsis, severe sepsis and septic shock, the number of patients with sepsis equals the number of all patients with sepsis including patients with severe sepsis and septic shock; bsee Additional file 2 for a detailed appraisal of the individual studies; cWalkey 2013 [25] only excluded patients after cardiothoracic surgery in a sensitivity analysis for identification of the risk factors, therefore we used this study only for the analysis of risk factors; dthe number of patients with sepsis excluding patients with cardiothoracic surgery or endocarditis during the sepsis hospitalization. AF: atrial fibrillation; ICD-9-CM: International Classification of Diseases-Ninth Revision-Clinical Modification; ICU: intensive care unit; n/a: not available.