Incidence, risk factors and outcomes of new-onset atrial fibrillation in patients with sepsis: a systematic review

Kuipers, Sanne; Klouwenberg, Peter MC Klein; Cremer, Olaf L

doi:10.1186/s13054-014-0688-5

Critical Care

Table 1 Overview of included studies

From: Incidence, risk factors and outcomes of new-onset atrial fibrillation in patients with sepsis: a systematic review

Reference	Setting	Number of patients with sepsis/total ^a	Detection method AF	Outcome	Methodological quality ^b
Arora et al., 2007 [16]	Single center, mixed ICU, Australia.	18/61	Prospective bedside detection +12-lead confirmation	n/a	Moderate
Christian et al., 2008 [17]	Single center, mixed ICU, USA.	274/274	Retrospective review of monitor data from a database developed for benchmarking	Death	Moderate
Gomez et al., 2012 [18]	Multicenter, mixed ICUs, Columbia.	100/100	Prospective detection using telemetry	n/a	Low
Goodman et al., 2007 [19]	Single center, mixed ICU, Israel.	149/611	Prospective bedside detection +12-lead confirmation.	n/a	Moderate
Meierhenrich et al., 2010 [20]	Single center, surgical ICU, Germany.	50/629	Prospective bedside detection +12-lead confirmation	Death	Moderate
Salman et al., 2008 [21]	Single center, mixed ICU, USA.	81/81	Retrospective review of monitor data from a hospital record database	Death	Moderate
Seguin et al., 2006 [22]	Single center, trauma ICU, France.	36/293	Prospective bedside detection +12-lead confirmation	n/a	Low
Seguin et al., 2004 [23]	Single center, surgical ICU, France.	107/460	Prospective bedside detection +12-lead confirmation	n/a	Moderate
Walkey et al., 2011 [24]	Multicenter, acute care hospital, USA.	49,082/49,082	Retrospective review from an administrative claims database using ICD-9-CM codes for detection of AF	Death	Moderate
Walkey et al., 2011 [24]	Multicenter, acute care hospital, USA.	49,082/49,082		Stroke	Moderate
Walkey et al., 2013 [25]^c	Multicenter, Medicare hospital, USA.	40,740/40,740^d	Retrospective review from an administrative claims database using ICD-9-CM codes for detection of AF	n/a	Moderate
Wells et al., 2011 [26]	Single center, medical ICU, USA.	465/1466	Retrospective review from an administrative database, detection of AF using telemetry	Death	Low

^aWhen studies differentiate between sepsis, severe sepsis and septic shock, the number of patients with sepsis equals the number of all patients with sepsis including patients with severe sepsis and septic shock; ^bsee Additional file 2 for a detailed appraisal of the individual studies; ^cWalkey 2013 [25] only excluded patients after cardiothoracic surgery in a sensitivity analysis for identification of the risk factors, therefore we used this study only for the analysis of risk factors; ^dthe number of patients with sepsis excluding patients with cardiothoracic surgery or endocarditis during the sepsis hospitalization. AF: atrial fibrillation; ICD-9-CM: International Classification of Diseases-Ninth Revision-Clinical Modification; ICU: intensive care unit; n/a: not available.

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