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Table 1 Characteristics of patients with hyper-, hypo- and normocoagulable ROTEM profiles at admission

From: Thromboelastometry and organ failure in trauma patients: a prospective cohort study

  All patients Hypercoagulable 1 Normocoagulable 2 Hypocoagulable 3 P value
N = 886 N = 63 N = 752 N = 71
Age (years) 38 [26–53] 44 [33–62] 38 [25–53] 38 [25–54] <0.05
Sex, male % (n) 78 (688) 60 (38) 80 (599) 72 (51) <0.001
Time to ED (minutes) 71 [53–90] 71 [46–86] 70 [53–88] 80 [60–100] 0.05
Trauma mechanism, blunt % (n) 81 (722) 81 (51) 82 (619) 86 (61) 0.69
Brain injury, % (n) 26 (233) 23 (14) 27 (193) 38 (26) 0.09
ISS 13 [6–25] 9 [5–17] 13 [5–25] 20 [10–39] <0.001
Systolic BP, (mmHg)* 131 (30) 136 (28) 131 (29) 122 (34) 0.06
Base excess (mEq/L) −1.4 [−4.0–0.6] −1.3 [−3.2–0.2] −1.2 [−3.7–0.8] −4.3 [−9.5—0.5] <0.001
RBC (units) 5 [3–8] 4 [3–5] 4 [3–8] 6 [4–11] <0.05
FFP (units) 4 [4–8] 3 [2–4] 4 [4–8] 6 [4–13] 0.001
PLT (units) 1 [1–2] 1 [1–1] 1 [1–2] 2 [1–5] <0.01
Cryoprecipitate 2 [2–2] NA 2 [2–2] 2.5 [2–5] 0.06
  1. All variables expressed as median and interquartile ranges [IQR]. *Expressed as mean and standard deviation (SD). 1Hypercoagulable G ≥11.7 dynes/cm2; 2normocoagulable G = 5–11.7 dynes/cm2; 3hypocoagulable G <5 dynes/cm2. ED: emergency department; ISS: injury severity score; BP: blood pressure; RBC: red blood cell; FFP: fresh frozen plasma; PLT: platelets; NA: not applicable.