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Figure 7 | Critical Care

Figure 7

From: Adenosine, lidocaine and Mg2+improves cardiac and pulmonary function, induces reversible hypotension and exerts anti-inflammatory effects in an endotoxemic porcine model

Figure 7

Renal function. A temporary impairment of renal function was observed during infusion of adenosine, lidocaine and magnesium (ALM), demonstrated by a decrease in urine output and creatinine clearance and an increase in plasma creatinine levels; however, this reversed after infusion was turned off. (A) Urine output during the study, measured hourly. (B) Plasma creatinine levels. (C) Creatinine clearance. (D) Urinary neutrophil gelatinase-associated lipocalin (NGAL)/creatinine ratio. *Significant difference at the end of the study. #Significantly different change over time between groups. †Significantly different development over time during infusion of ALM. ¥Significant difference before/after cessation ALM infusion. Data presented as median (95% confidence interval), except for creatinine clearance that is presented as mean (95% confidence interval). LPS, lipopolysaccharide.

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