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Figure 6 | Critical Care

Figure 6

From: Adenosine, lidocaine and Mg2+improves cardiac and pulmonary function, induces reversible hypotension and exerts anti-inflammatory effects in an endotoxemic porcine model

Figure 6

Cardiac function. During infusion of adenosine, lidocaine and magnesium (ALM), the end systolic pressure was significantly lower resulting in an improved arterial–ventricular coupling. Furthermore, systolic and diastolic function evaluated by dP/dt max and dP/dt min respectively was improved at the end of the study in the ALM group. (A) End systolic pressure. (B) Maximum rate of pressure development over time (dP/dt max). (C) Maximum rate of pressure decrease over time (dP/dt min). (D) Ventricular–arterial coupling. *Significant difference at the end of the study. #Significant different change over time between groups. †Significant different mean/median level during infusion of ALM. ¥Significant difference before/after cessation of ALM infusion. Data presented as median (95% confidence interval). Ea, arterial elastance; Ees, end systolic elastance (end systolic pressure–volume relationship); LPS, lipopolysaccharide.

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Critical Care

ISSN: 1364-8535