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Figure 4 | Critical Care

Figure 4

From: Adenosine, lidocaine and Mg2+improves cardiac and pulmonary function, induces reversible hypotension and exerts anti-inflammatory effects in an endotoxemic porcine model

Figure 4

Pulmonary function. Infusion of adenosine, lidocaine and magnesium (ALM) improved pulmonary function, indicated by a lower mean pulmonary arterial pressure, a lower alveolar–arterial oxygen difference, a lower wet/dry ratio and a higher PaO2/FiO2 ratio. (A) Mean pulmonary arterial pressure. (B) Alveolar–arterial oxygen difference. (C) PaO2/FiO2 ratio. (D) Pulmonary wet/dry ratio. *Significant difference at the end of the study. #Significantly different change over time between groups. ¥Significant difference before/after cessation ALM infusion. Mean pulmonary arterial pressure and PAO2–PaO2 difference are presented as median (95% confidence interval), while the PaO2/FiO2 ratio is presented as mean (95% confidence interval). Pulmonary wet/dry ratio presented as mean and individual values. FiO2, inspired fraction of oxygen; LPS, lipopolysaccharide; PaO2, arterial partial pressure of oxygen; PAO2, alveolar partial pressure of oxygen.

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