From: The early antibiotic therapy in septic patients - milestone or sticking point?
● | Early quantitative resuscitation of the septic patient during the first 6 hours after recognition (1C) |
● | Blood cultures before antibiotic therapy (1C) |
● | Imaging studies performed promptly to confirm a potential source of infection (UG) |
● | Administration of broad-spectrum antimicrobials therapy within 1 hour of the recognition of septic shock (1B) and severe sepsis without septic shock (1C) as the goal of therapy |
● | Reassessment of antimicrobial therapy daily for de-escalation, when appropriate (1B) |
● | Infection source control with attention to the balance of risks and benefits of the chosen method within 12 hours of diagnosis (1C) |