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Table 1 Demographic, illness severity and physiological data a

From: Determining the mechanisms underlying augmented renal drug clearance in the critically ill: use of exogenous marker compounds

Variable Data ( N =20)
Age, yr, mean (95% CI) 36.7 (29.2 to 44.1)
Males, n (%) 12 (60.0)
Height, m, mean (95% CI) 1.74 (1.68 to 1.79)
Weight, kg, mean (95% CI) 80.2 (70.8 to 89.5)
Body surface area, m2, mean (95% CI) 1.94 (1.81 to 2.07)
Days in ICU before sampling, mean (95% CI) 4.90 (3.74 to 6.06)
APACHE II score, mean (95% CI) 17.3 (13.7 to 20.8)
Diagnosis, n (%)  
 Burns 3 (15.0)
 Trauma (including head injury) 10 (50.0)
 Neurological 3 (15.0)
 Sepsis 3 (15.0)
 Other 1 (5.0)
Mechanically ventilated, n (%) 19 (95.0)
Receiving vasopressor infusion, n (%) 3 (15.0)
Pre-dose HR, beats/min, mean (95% CI) 100 (90.8 to 110)
Pre-dose MAP, mmHg, mean (95% CI) 89.4 (83.0 to 95.8)
Plasma CR, μmol/L, mean (95% CI) 64.5 (53.2 to 75.7)
Urinary CR, mmol/L, mean (95% CI) 5.93 (4.02 to 7.85)
24-hr urinary volume, L, mean (95% CI) 3.10 (2.35 to 3.85)
Urinary pH, mean (95% CI), n =16 6.16 (5.75 to 6.57)
24-hr fluid balance, ml, mean (95% CI) 700 (−126 to 1,527)
24-hr CLCR, ml/min, mean (95% CI) 168 (139 to 197)
CKD-EPI eGFR, ml/min, mean (95% CI) 128 (113 to 144)
  1. aAPACHE, Acute Physiology and Chronic Health Evaluation; CI, Confidence interval; CLCR, Creatinine clearance; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; CR, Creatinine; eGFR, Estimated glomerular filtration rate; HR, Heart rate; ICU, Intensive care unit; MAP, Mean arterial pressure.