Variables | Group | SOP | SOP + LS | CLP | CLP + Veh | CLP + LS |
---|---|---|---|---|---|---|
pH | 0 h | 7.6 ± 0.01 | 7.5 ± 0.01 | 7.6 ± 0.02 | 7.6 ± 0.01 | 7.6 ± 0.01 |
9 h | 7.5 ± 0.01 | 7.5 ± 0.01 | 7.6 ± 0.01 | 7.6 ± 0.02 | 7.6 ± 0.02 | |
18 h | 7.6 ± 0.01 | 7.6 ± 0.01 | 7.5 ± 0.01 | 7.5 ± 0.03 | 7.6 ± 0.01 | |
PaCO2, mmHg | 0 h | 34 ± 1.7 | 37 ± 2.3 | 32 ± 1.7 | 34 ± 0.4 | 35 ± 0.7 |
9 h | 36 ± 1 | 37 ± 1.8 | 22 ± 0.9* | 24 ± 1.4* | 24 ± 1.7* | |
18 h | 31 ± 1.2 | 32 ± 1.4 | 20 ± 1.3* | 21 ± 1.9* | 28 ± 1.4†| |
HCO3-, mM | 0 h | 30 ± 0.7 | 31.1 ± 1.1 | 27.9 ± 0.9 | 30 ± 0.7 | 29.9 ± 0.6 |
9 h | 29.4 ± 0.6 | 29.4 ± 1.1 | 20.8 ± 0.8* | 22.1 ± 1.1* | 23.2 ± 0.8* | |
18 h | 27.6 ± 0.7 | 28.5 ± 1.4 | 16.7 ± 1* | 15.4 ± 1.2* | 24.5 ± 1†| |
Base excess, mM | 0 h | 7.8 ± 0.5 | 8.4 ± 0.7 | 7.3 ± 0.2 | 7.9 ± 0.8 | 7.5 ± 0.5 |
9 h | 6.7 ± 0.5 | 6.7 ± 0.7 | 1.2 ± 0.7* | 2.2 ± 1.1* | 3.6 ± 0.5* | |
18 h | 5.4 ± 0.5 | 6.7 ± 1.1 | -3.2 ± 0.8* | -5.5 ± 1.3* | 3.2 ± 0.9*†| |
Potassium, mM | 0 h | 3.7 ± 0.1 | 3.9 ± 0.1 | 3.8 ± 0.1 | 3.8 ± 0.1 | 3.9 ± 0.1 |
9 h | 3.6 ± 0.1 | 4 ± 0.1 | 3.9 ± 0.1 | 3.9 ± 0.2 | 3.9 ± 0.1 | |
18 h | 3.6 ± 0.1 | 3.7 ± 0.2 | 4.9 ± 0.2* | 5.2 ± 0.4* | 3.8 ± 0.1†|