Table 2 Characteristics of patients undergoing ECMO and controls
ECMO (n = 11) | Controls (n = 11) | |
|---|---|---|
Male, n | 4 | 5 |
Age, years | 43 (19 to 59) | 55 (24 to 64) |
Estimated weight, kg | 70 (46 to 85) | 70 (47 to 95) |
Estimated body mass index, kg/m2 | 26 (18-29) | 24 (18-29) |
Medical admission, n | 9 | 8 |
APACHE II score on ICU admission | 22 (3 to 33) | 18 (5 to 34) |
Mechanical ventilation on ICU admission | 9 | 7 |
SOFA score on the first day of therapy | 11 (5 to 13) | 11 (2 to 15) |
Time from ICU admission to ECMO, days | 3 (0 to 9) | NA |
Time from ICU admission to vancomycin therapy, days | 7 (4 to 18) | 4 (0 to 8) * |
Mechanical ventilation on the first day of therapy | 11 | 7 |
Fluid balance (the day preceding the loading dose), mL/24 h | 1959 (-1404 to 5877) | 2153 (-1592 to 9686) |
Albumin concentration (before the loading dose), g/dL | 2.6 (2 to 3.3) | 2.8 (2 to 3.8) |
Protein concentration (before the loading dose), g/dL | 4.2 (2.8 to 4.8) | 4.6 (3.4 to 6.4) |
Lactate level (before the loading dose), mmol/L | 1.1 (0.5 to 17.9) | 1.8 (0.7 to 7.9) |
CrCl on the first day of therapy, mL/minute (n = 4) | 64 (39 to 99) | 61 (46 to 109) |
CRRT intensity, mL/kg/h (n = 7) | 38 (19 to 53) | 42 (20 to 50) |
Reason for ECMO initiation | ||
Cardiogenic shock/ARDS/Sepsis, n | 5/4/2 | 2/4/5 |
VA ECMO/VV ECMO, n | 5/6 | NA |
Overall ICU mortality, n | 6 | 3 |
Comorbidities | ||
CVD | 2 | 1 |
COPD/asthma | 3 | 2 |
Diabetes | 3 | 2 |
Previous serum creatinine >2.0 mg/dL | 1 | 0 |
Liver disease | 0 | 1 |
Solid organ transplant | 2 | 2 |
Chronic immunosuppressive therapy | 3 | 3 |
Neutropenia | 1 | 2 |