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Table 2 Effects of volume expansion in hemodynamic variables according to mean arterial pressure increase a

From: Dynamic arterial elastance as a predictor of arterial pressure response to fluid administration: a validation study

 

Before volume expansion

After volume expansion

P -value b

CO, L/min

   

  Responders

4.9 ± 2.2

5.8 ± 2.5c

0.581

  Non-responders

5.9 ± 2.3

6.8 ± 2.6c

Heart rate, beats/min

   

  Responders

91 ± 21

86 ± 19c

0.036

  Non-responders

92 ± 17

90 ± 17c

 

SV, ml

   

  Responders

56 ± 24

69 ± 26c

0.971

  Non-responders

65 ± 27

77 ± 33c

 

CPO, W

   

  Responders

0.7 ± 0.3d

1.0 ± 0.4c

<0.001

  Non-responders

0.9 ± 0.3

1.1 ± 0.4c

 

MAP, mmHg

   

  Responders

67 ± 15d

80 ± 18c

<0.001

  Non-responders

74 ± 12

76 ± 12c

 

SAP, mmHg

   

  Responders

102 ± 18d

128 ± 22c

<0.001

  Non-responders

113 ± 18

118 ± 20*

 

DAP, mmHg

   

  Responders

51 ± 13

57 ± 14c

<0.001

  Non-responders

55 ± 11

55 ± 11

 

PP, mmHg

   

  Responders

51 ± 17

70 ± 20c

<0.001

  Non-responders

58 ± 15

64 ± 17c

 

PPV, %

   

  Responders

18 ± 7d

9 ± 5c

<0.001

  Non-responders

11 ± 5

8 ± 4c

 

SVV, %

   

  Responders

17 ± 8

15 ± 7c

0.135

  Non-responders

18 ± 7

15 ± 5c

 
  1. aResponders are defined by a mean arterial pressure (MAP) increase ≥10%). Data are expressed as mean ± SD. bP-values refer to group (responder vs. non-responder) and time (preinfusion vs. postinfusion) interaction using analysis of variance for repeated measurements. cP <0.05 vs. before volume expansion. P <0.05 vs. non-responders. CO, Cardiac output; CPO, Cardiac power output (mean arterial pressure × cardiac output/451); DAP, Diastolic arterial pressure; MAP, Mean arterial pressure; PP, Pulse pressure (systolic pressure minus diastolic pressure); PPV, Arterial pulse pressure variation; SAP, Systolic arterial pressure; SV, Stroke volume; SVV, Stroke volume variation.