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Table 3 Logistic regression analysis of 28-day mortality in 363 septic patients, with initial S cv O 2 value below 70 % adjusted for the other confounders

From: Prevalence of low central venous oxygen saturation in the first hours of intensive care unit admission and associated mortality in septic shock patients: a prospective multicentre study

Covariables a

Adjusted odds ratio b

95% CI

P -value

SAPSII (for each 1 point increase)

1.05

1.03, 1.07

<0.00001

Initial ScvO2 < 70%

3. 60

1.76, 7.36

0.0004

Arterial lactate (for each 1 mmol/L increase)

1.18

1.06, 1.32

0.002

Initial arterial partial pressure in CO2 (for each 1 mmHg increase)

1.04

1.01, 1.06

0.003

McCabe class 1 (versus class 0)

2.58

1.31, 5.10

0.006

Abdominal sepsis

2.56

1.25, 5.23

0.010

McCabe class 2 (versus class 0)

3.09

1.24, 7.72

0.016

Male gender

2.14

1.11, 4.13

0.022

Initial body temperature (for each 1C° increase)

0.78

0.62, 0.98

0.031

Exposure to ACE inhibitors or ARB in the past 48 hours

0.50

0.26, 0.98

0.044

  1. aAll covariables entered in the model were variables linked to day-28 mortality with P <0.05 on univariate analysis, and selected using the backward method. bFor each continuous covariable odds ratios are given per each unit of the given covariable. ACE, angiotensin-converting enzyme; ARB, angiotensin II receptor blockers; SAPSII, Simplified acute physiology score; ScvO2, central venous oxygen saturation.
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