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Table 2 Univariate analysis of mortality according to post-return of spontaneous circulation factors

From: Post return of spontaneous circulation factors associated with mortality in pediatric in-hospital cardiac arrest: a prospective multicenter multinational observational study

 

Patients, number

Patients, %

Mortality, %

Odds ratio

95% CI

P -value

Mechanical ventilation

      

No

42

6.1

41.2

1

  

Yes

173

93.9

45

3.273

0.713 to 15.027

0.127

Vasoactive drugs

      

No

79

31.3

29.1

1

  

Yes

173

68.7

42.8

1.820

1.028 to 3.222

0.040

Vasoactive-inotropic score

      

<14

62

40.3

29

0.390

  

>14

92

59.7

51

2.564

1.288 to 5.050

0.007

Electrocardiographic rhythm after ROSC

      

Sinus rhythm

230

72.8

43.5

1

  

Other rhythms

86

27.2

53.5

1.495

0.909 to 2.459

0.113

Recovery of spontaneous breathing

      

Yes

86

26

22.1

1

  

No

245

74

57.1

4.694

2.659 to 8.333

0.001

pH 1 h

      

7.30 to 7.50

96

37.1

37.5

1

  

<7.30

154

59.5

48.7

1.582

0.941 to 2.662

0.084

>7.50

9

3.5

22.2

0.476

0.094 to 2.418

0.371

PaO 2 1 h

      

60 to 200 mmHg

123

48.6

44.7

1

  

<60 mmHg

96

37.9

43.8

0.962

0.562 to 1.646

0.887

>200 mmHg

34

13.4

32.4

0.591

0.265 to 1.318

0.199

PaCO 2 1 h

      

30 to 50 mmHg

133

52.2

33.1

1

  

<30 mmHg

37

14.5

62.2

3.323

1.560 to 7.079

0.002

>50 mmHg

85

33.3

52.9

2.276

1.302 to 3.978

0.004

CO 3 H 1 h

      

20 to 26 mEq/L

75

31.1

36

1

  

<20 mEq/L

118

49

46.6

1.552

0.857 to 2.812

0.147

>26 mEq/L

48

19.9

41.7

1.27

0.604 to 2.669

0.528

Base excess 1 h

      

+4 to -4

48

20.6

37.5

1

  

<-4

154

66.1

46.8

1.463

0.753 to 2.844

0.261

> + 4

31

13.3

41.9

1.204

0.479 to 3.027

0.694

FiO 2 1 h

      

<0.50

42

16.7

12.1

1

  

0.50 to 0.79

41

16.3

12.9

1.150

0.468 to 2.847

0.756

≥0.80

169

67.1

75

2.120

1.044 to 4.311

0.038

PaO 2 /FiO 2 1 h

      

>300

166

16.7

45.5

1

  

200 to 300

37

11.7

25.8

0.417

0.154 to 1.134

0.087

<200

28

71.6

46

1.024

0.530 to 1.978

0.945

Lactic acid 1 h

      

<2 mmol/L

27

19.9

22.2

1

  

2 to 5 mmol/L

39

28.7

28.2

1.375

0.438 to 4.318

0.585

>5 mmol/L

70

51.5

51.4

3.706

1.335 to 10.29

0.012

pH 24 h

      

7.30 to 7.50

158

75.6

27.8

1

  

<7.30

39

18.7

53.8

3.023

1.472 to 6.205

0.003

>7.50

70

5.7

33.3

1.295

0.371 to 4.520

0.685

PaO 2 24 h

      

60 to 200 mmHg

121

59

32.2

1

  

<60 mmHg

70

34.1

28.6

0.841

0.442 to 1.601

0.598

>200 mmHg

14

6.8

57.1

2.803

0.910 to 8.636

0.073

PaCO 2 24 h

      

30 to 50 mmHg

123

68.3

25.2

1

  

<30 mmHg

14

7.8

35.7

1.649

0.513 to 5.294

0.401

>50 mmHg

43

23.9

51.2

3.109

1.508 to 6.409

0.002

CO 3 H 24 h

      

20 to 26 mEq/L

90

43.9

36.7

1

  

<20 mEq/L

41

20

43.9

1.352

0.638 to 2,865

0.432

>26 mEq/L

74

36.1

24.3

0.555

0.281 to 1,099

0.091

Base excess 24 h

      

+4 to -4

90

48.4

30

1

  

<-4

52

28

40.4

1.581

0.774 to 3.229

0.209

> + 4

44

23.7

22.7

0.686

0.297 to 1.585

0.378

FiO 2 24 h

      

<0.50

80

41.9

22.1

   

0.50 to 0.79

48

25.1

25

2.376

1.051 to 5.371

0.038

≥0.80

63

33

52.9

5.778

2.726 to 12.245

0.001

PaO 2 /FiO 2 24 h

      

>300

116

18.2

21.6

1

  

200 to 300

34

16.3

30.3

2.327

0.988 to 5.481

0.053

< 00

28

65.5

39.1

1.576

0.536 to 4.636

0.408

Lactic acid 24 h

      

<2 mmol/L

73

59.3

23.3

1

  

2 to 5 mmol/L

29

23.6

37.9

2.013

0.798 to 5.081

0.139

>5 mmol/L

21

17.1

47.6

2.995

1.086 to 8.254

0.034

Lactic acid clearance

      

>50%

56

55.9

28.8

1

  

>50%

43

44.1

30.8

1.099

0.497 to 2.433

0.841

  1. Significant values marked in bold. Lactid acid clearance: (lactate after ROSC minus lactate 24 hours after ROSC) × 100/lactate after ROSC. ROSC, return of spontaneous of circulation; FiO2, inspired oxygen fraction; PaO2, arterial partial pressure of oxygen.