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Table 2 Univariate analysis of mortality according to post-return of spontaneous circulation factors

From: Post return of spontaneous circulation factors associated with mortality in pediatric in-hospital cardiac arrest: a prospective multicenter multinational observational study

  Patients, number Patients, % Mortality, % Odds ratio 95% CI P -value
Mechanical ventilation       
No 42 6.1 41.2 1   
Yes 173 93.9 45 3.273 0.713 to 15.027 0.127
Vasoactive drugs       
No 79 31.3 29.1 1   
Yes 173 68.7 42.8 1.820 1.028 to 3.222 0.040
Vasoactive-inotropic score       
<14 62 40.3 29 0.390   
>14 92 59.7 51 2.564 1.288 to 5.050 0.007
Electrocardiographic rhythm after ROSC       
Sinus rhythm 230 72.8 43.5 1   
Other rhythms 86 27.2 53.5 1.495 0.909 to 2.459 0.113
Recovery of spontaneous breathing       
Yes 86 26 22.1 1   
No 245 74 57.1 4.694 2.659 to 8.333 0.001
pH 1 h       
7.30 to 7.50 96 37.1 37.5 1   
<7.30 154 59.5 48.7 1.582 0.941 to 2.662 0.084
>7.50 9 3.5 22.2 0.476 0.094 to 2.418 0.371
PaO 2 1 h       
60 to 200 mmHg 123 48.6 44.7 1   
<60 mmHg 96 37.9 43.8 0.962 0.562 to 1.646 0.887
>200 mmHg 34 13.4 32.4 0.591 0.265 to 1.318 0.199
PaCO 2 1 h       
30 to 50 mmHg 133 52.2 33.1 1   
<30 mmHg 37 14.5 62.2 3.323 1.560 to 7.079 0.002
>50 mmHg 85 33.3 52.9 2.276 1.302 to 3.978 0.004
CO 3 H 1 h       
20 to 26 mEq/L 75 31.1 36 1   
<20 mEq/L 118 49 46.6 1.552 0.857 to 2.812 0.147
>26 mEq/L 48 19.9 41.7 1.27 0.604 to 2.669 0.528
Base excess 1 h       
+4 to -4 48 20.6 37.5 1   
<-4 154 66.1 46.8 1.463 0.753 to 2.844 0.261
> + 4 31 13.3 41.9 1.204 0.479 to 3.027 0.694
FiO 2 1 h       
<0.50 42 16.7 12.1 1   
0.50 to 0.79 41 16.3 12.9 1.150 0.468 to 2.847 0.756
≥0.80 169 67.1 75 2.120 1.044 to 4.311 0.038
PaO 2 /FiO 2 1 h       
>300 166 16.7 45.5 1   
200 to 300 37 11.7 25.8 0.417 0.154 to 1.134 0.087
<200 28 71.6 46 1.024 0.530 to 1.978 0.945
Lactic acid 1 h       
<2 mmol/L 27 19.9 22.2 1   
2 to 5 mmol/L 39 28.7 28.2 1.375 0.438 to 4.318 0.585
>5 mmol/L 70 51.5 51.4 3.706 1.335 to 10.29 0.012
pH 24 h       
7.30 to 7.50 158 75.6 27.8 1   
<7.30 39 18.7 53.8 3.023 1.472 to 6.205 0.003
>7.50 70 5.7 33.3 1.295 0.371 to 4.520 0.685
PaO 2 24 h       
60 to 200 mmHg 121 59 32.2 1   
<60 mmHg 70 34.1 28.6 0.841 0.442 to 1.601 0.598
>200 mmHg 14 6.8 57.1 2.803 0.910 to 8.636 0.073
PaCO 2 24 h       
30 to 50 mmHg 123 68.3 25.2 1   
<30 mmHg 14 7.8 35.7 1.649 0.513 to 5.294 0.401
>50 mmHg 43 23.9 51.2 3.109 1.508 to 6.409 0.002
CO 3 H 24 h       
20 to 26 mEq/L 90 43.9 36.7 1   
<20 mEq/L 41 20 43.9 1.352 0.638 to 2,865 0.432
>26 mEq/L 74 36.1 24.3 0.555 0.281 to 1,099 0.091
Base excess 24 h       
+4 to -4 90 48.4 30 1   
<-4 52 28 40.4 1.581 0.774 to 3.229 0.209
> + 4 44 23.7 22.7 0.686 0.297 to 1.585 0.378
FiO 2 24 h       
<0.50 80 41.9 22.1    
0.50 to 0.79 48 25.1 25 2.376 1.051 to 5.371 0.038
≥0.80 63 33 52.9 5.778 2.726 to 12.245 0.001
PaO 2 /FiO 2 24 h       
>300 116 18.2 21.6 1   
200 to 300 34 16.3 30.3 2.327 0.988 to 5.481 0.053
< 00 28 65.5 39.1 1.576 0.536 to 4.636 0.408
Lactic acid 24 h       
<2 mmol/L 73 59.3 23.3 1   
2 to 5 mmol/L 29 23.6 37.9 2.013 0.798 to 5.081 0.139
>5 mmol/L 21 17.1 47.6 2.995 1.086 to 8.254 0.034
Lactic acid clearance       
>50% 56 55.9 28.8 1   
>50% 43 44.1 30.8 1.099 0.497 to 2.433 0.841
  1. Significant values marked in bold. Lactid acid clearance: (lactate after ROSC minus lactate 24 hours after ROSC) × 100/lactate after ROSC. ROSC, return of spontaneous of circulation; FiO2, inspired oxygen fraction; PaO2, arterial partial pressure of oxygen.