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Table 10 Model coefficients for final models (complete case data)

From: Predictive models for kidney disease: improving global outcomes (KDIGO) defined acute kidney injury in UK cardiac surgery

 

Any-stage AKI

Stage-3 AKI

 

Odds ratio

95% CI

P -value

Odds ratio

95% CI

P-value

Age, years

      

 <60

1.00

     

 60 to 74

1.53

(1.35, 1.73)

    

 ≥75

2.19

(1.89, 2.54)

<0.001

   

Sex

      

 Male

1.00

  

1.00

  

 Female

0.53

(0.48, 0.59)

<0.001

0.42

(0.34, 0.51)

<0.001

Body mass index

      

 <20.0

0.80

(0.64, 0.99)

 

0.54

(0.35, 0.82)

 

 20.0 to 24.9

0.80

(0.72, 0.88)

 

0.84

(0.68, 1.04)

 

 25.0 to 29.9

1.00

  

1.00

  

 30.0 to 34.9

1.75

(1.57, 1.95)

 

1.81

(1.44, 2.27)

 

 35.0+

2.08

(1.76, 2.47)

<0.001

2.71

(1.94, 3.79)

<0.001

Smoking status

      

 Never smoked

1.00

     

 Ex smoker

1.09

(1.00, 1.20)

    

 Current smoker

1.41

(1.22, 1.64)

<0.001

   

Dyspnoea

      

 NYHA 1

1.00

     

 NHYA 2

1.05

(0.94, 1.17)

    

 NYHA 3

1.29

(1.14, 1.45)

    

 NYHA 4

1.44

(1.20, 1.74)

<0.001

   

Preoperative diabetes

      

 No

1.00

  

1.00

  

 Yes

1.40

(1.27, 1.55)

<0.001

1.91

(1.59, 2.31)

<0.001

Peripheral vascular disease

      

 No

1.00

     

 Yes

1.35

(1.20, 1.52)

<0.001

   

Hypertension

      

 No

1.00

     

 Yes

1.28

(1.17, 1.40)

<0.001

   

Haemoglobin

      

 <10.0

1.68

(1.31, 2.17)

 

2.98

(2.05, 4.32)

 

 10.0 to 11.9

1.71

(1.53, 1.91)

 

2.53

(2.08, 3.07)

 

 12.0+

1.00

 

<0.001

1.00

 

<0.001

Glomerular filtration rate

      

 <30.0

4.58

(3.69, 5.69)

 

9.50

(6.89, 13.10)

 

 30.0 to 59.9

2.25

(2.04, 2.49)

 

2.56

(2.10, 3.13)

 

 60.0 to 89.9

1.00

  

1.00

  

 90.0+

0.82

(0.72, 0.95)

<0.001

0.43

(0.30, 0.62)

<0.001

Critical preoperative event

      

 No

      

 Yes

   

3.35

(2.35, 4.78)

<0.001

Catheter to surgery

      

 Within 24 h

1.22

(0.91, 1.64)

 

1.58

(1.03, 2.43)

 

 >24 hrs this admission

0.78

(0.71, 0.86)

 

0.71

(0.59, 0.85)

 

 >24 hrs previous admission

1.00

 

<0.001

1.00

 

<0.001

Triple vessel disease

      

 No

1.00

     

 Yes

1.22

(1.10, 1.34)

<0.001

   

Ejection fraction

      

 Good (50+ %)

1.00

     

 Fair (30-49%)

1.24

(1.14, 1.36)

    

 Poor (<30%)

1.42

(1.20, 1.67)

<0.001

   

Operative priority

      

 Elective

1.00

     

 Urgent

1.43

(1.30, 1.58)

    

 Emergency/salvage

2.45

(1.74, 3.43)

<0.001

   

Cardiac procedures

      

 CABG only

1.00

  

1.00

  

 Valve only

1.43

(1.24, 1.65)

 

1.50

(1.17, 1.92)

 

 CABG+valve

1.89

(1.67, 2.15)

 

2.15

(1.72, 2.70)

 

 Other/multiple

1.82

(1.57, 2.11)

<0.001

2.92

(2.30, 3.72)

<0.001

Constant

0.05

(0.04, 0.06)

<0.001

0.01

(0.01, 0.02)

<0.001

  1. Models are the initial models (variables P <0.001 in models adjusting for main effects). AKI, acute kidney injury; NYHA, New York Heart Association; CABG, coronary artery bypass graft; Haemoglobin, g/dL; GFR, mL/min.
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