Table 3 Increasing cohort and per-patient median S _I during cool and warm periods as per six-hour blocks of data, where the P values compare successive six-hour blocks as shown in the first column for both the overall cohort and per-patient median values

Block 1-2 (C)

35.1

<0.05

26.4

<0.05

(0–6 vs. 6–12 hr)

Block 2–3 (C)

19.2

<0.05

31.1

<0.05

(6–12 vs. 12–18 hr)

Block 3-4 (C)

31.8

<0.05

42.4

<0.05

(12-18 vs. 18-24 hr)

Block 4-5 (C-W)

23.4

<0.05

18.3

<0.05

(18-24 vs. 24-30 hr)

Block 5-6 (W)

23.9

<0.05

23.2

<0.05

(24-30 vs. 30-36 hr)

Block 6-7 (W)

13.1

0.06

15.8

0.2

(30-36 vs. 36-42 hr)

Block 7-8 (W)

4.4

0.4

3.2

0.5

(36-42 vs. 42-48 hr)