Early N = 245 | Late N = 244 | P-value | |
---|---|---|---|
28-day mortality | 42 (17%; 13 to 22) | 47 (19%; 14 to 25) | 0.5436 |
90-day mortality | 63 (26%; 20 to 31) | 73 (30%;24 to 36) | 0.2996 |
Hospital mortality | 67 (27%; 22 to 33) | 78 (32%; 26 to 38) | 0.2634 |
Days free of mechanical ventilation, 28-day | 11 (0, 22) | 9 (0, 22) | 0.0529 |
Days free of mechanical ventilation, 90-day | 73 (0 to 84) | 71 (0 to 84) | 0.0546 |
Duration of sedation, days, n | 11 (2 to 92) | 14 (0 to 79) | 0.0194 |
ICU length of stay, days, n | 22 (6 to 101) | 22.5 (6 to 174) | 0.3088 |
Other characteristics related to mechanical ventilation and tracheotomy | |||
Weaning protocol applied in intubated patients | 125 (51%; 45 to 57) | 141 (58%; 52 to 64) | 0.1331 |
Failed extubation (reintubated) | 38 (16%; 11 to 21) | 27 (11%; 7 to 16) | 0.1477 |
Days of intubation in tracheotomized patients | 7 (6 to 29) | 14 (9 to 47) | 0.0009 |
Days of intubation in successfully extubated patients | 10 (8 to 18) | 10 (8 to 21) | 0.8921 |
Patients sedated, n (%) | 234 (96%; 92 to 98) | 235 (96%; 93 to 98) | 0.6546 |
Deep sedation with neuro-blocker drugs | 36 (15%; 11 to 20) | 52 (21%; 16 to 27) | 0.0568 |
Maximum positive end-expiratory pressure | 7 (0 to 16) | 7 (3 to 16) | 0.9473 |
Ventilation-associated pneumonia | 33 (13%; 9 to 19) | 23 (9%; 6 to 15) | 0.1604 |
Early complications of tracheotomy | 2 (1.2%: 0.2 to 4) | 9 (6.7%; 3 to 12) | 0.0139 |