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Table 2 Risk of bias assessed using the SIGN score

From: The effects of goal-directed fluid therapy based on dynamic parameters on post-surgical outcome: a meta-analysis of randomized controlled trials

Study SIGN score SIGN comment
Benes, 2010 [38] Europe ++ -
Buettner, 2008 [11] Europe - Blinding and concealment not clear
Forget, 2010 [37] Europe ++ -
Goepfert, 2013 [36] Europe ++ -
Harten, 2008 [35] Europe - Blinding not clear, outcomes not defined
Kapoor, 2008 [39] India - Randomization and blinding not clear, outcomes not defined
Lopes, 2007 [10] Brazil ++ -
Mayer, 2010 [40] Europe + Randomization not clear
Ramsingh, 2013 [34] USA + Intention-to-treat analysis not performed.
Salzwedel, 2013 [30] Europe ++ Multicentric trial
Sheeren, 2013 [33] Europe + Intention-to-treat analysis not performed, multicentric trial
Zhang Ju, 2012 [32] China + Intention-to-treat analysis not performed
Zhang Ji, 2013 [31] China - Randomization and blinding not clear, outcomes not defined
Zheng, 2013 [29] China ++ -
  1. SIGN: The Scottish Intercollegiate Guidelines Network.