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Table 2 Baseline characteristics and outcomes

From: Rapid Induction of COOLing in Stroke Patients (iCOOL1): a randomised pilot study comparing cold infusions with nasopharyngeal cooling

  Cold infusion Nasopharyngeal cooling P-value
Patients; number 10 10  
Female; number (%) 4 (40%) 5 (50%) n.s.a
Age, years; mean ± STD 65.4 ± 7.4 55.7 ± 11.5 0.038b
Weight, kg 83.5 ± 17.7 80.3 ± 12.7 n.s.b
Height, cm 173.1 ± 10.1 172 ± 10 n.s.b
Body mass index, kg/m2 27.9 ± 5.9 27.3 ± 2.4 n.s.b
Body surface aread, m2 2 ± 0.2 2 ± 0.2 n.s.b
Time from symptom onset to treatment, hours 69.4 ± 25.2 67.1 ± 31.9 n.s.b
Stroke type; number (%)    n.s.a
Ischaemic 7 (70%) 4 (40%)  
ICH 2 (20%) 5 (50%)  
SAH 1 (10%) 1 (10%)  
Scores    
Premorbid mRS; number (%)    n.s.c
0 7 (70%) 7 (70%)  
1 2 (20%) 2 (20%)  
2 1 (10%) 1 (10%)  
NIHSS admission; median (IQR) 14.5 (6.75-24.75) 26.5 (17.5-38) n.s.c
mRS follow-up median (IQR) 4.5 (3.75-6) 4.5 (3-6) n.s.c
Risk factors; number (%)    
Diabetes mellitus 0 (0%) 3 (30%) n.s.a
Arterial hypertension 8 (80%) 8 (80%) n.s.a
Hypercholesterolaemia 0 (0%) 1 (10%) n.s.a
Atrial fibrillation 2 (20%) 0 (0%) n.s.a
  1. aFisher's exact test; bStudent’s t-test; cMann-Whitney U test.; dMosteller formula. ICH, intracerebral haemorrhage; IQR, interquartile range; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; n.s. non-significant; SAH, subarachnoid haemorrhage; STD, standard deviation.