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Table 2 Baseline characteristics and outcomes

From: Rapid Induction of COOLing in Stroke Patients (iCOOL1): a randomised pilot study comparing cold infusions with nasopharyngeal cooling

 

Cold infusion

Nasopharyngeal cooling

P-value

Patients; number

10

10

 

Female; number (%)

4 (40%)

5 (50%)

n.s.a

Age, years; mean ± STD

65.4 ± 7.4

55.7 ± 11.5

0.038b

Weight, kg

83.5 ± 17.7

80.3 ± 12.7

n.s.b

Height, cm

173.1 ± 10.1

172 ± 10

n.s.b

Body mass index, kg/m2

27.9 ± 5.9

27.3 ± 2.4

n.s.b

Body surface aread, m2

2 ± 0.2

2 ± 0.2

n.s.b

Time from symptom onset to treatment, hours

69.4 ± 25.2

67.1 ± 31.9

n.s.b

Stroke type; number (%)

  

n.s.a

Ischaemic

7 (70%)

4 (40%)

 

ICH

2 (20%)

5 (50%)

 

SAH

1 (10%)

1 (10%)

 

Scores

   

Premorbid mRS; number (%)

  

n.s.c

0

7 (70%)

7 (70%)

 

1

2 (20%)

2 (20%)

 

2

1 (10%)

1 (10%)

 

NIHSS admission; median (IQR)

14.5 (6.75-24.75)

26.5 (17.5-38)

n.s.c

mRS follow-up median (IQR)

4.5 (3.75-6)

4.5 (3-6)

n.s.c

Risk factors; number (%)

   

Diabetes mellitus

0 (0%)

3 (30%)

n.s.a

Arterial hypertension

8 (80%)

8 (80%)

n.s.a

Hypercholesterolaemia

0 (0%)

1 (10%)

n.s.a

Atrial fibrillation

2 (20%)

0 (0%)

n.s.a

  1. aFisher's exact test; bStudent’s t-test; cMann-Whitney U test.; dMosteller formula. ICH, intracerebral haemorrhage; IQR, interquartile range; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; n.s. non-significant; SAH, subarachnoid haemorrhage; STD, standard deviation.