Table 5 Sedative consumption and differences between periods a
| Â | Preintervention | Postintervention | Â | Â |
|---|---|---|---|---|
| Â | October 2010 to September 2011 | October 2011 to October 2012 | Mean difference (95% CI) | P-value |
Monthly average midazolam consumption (mg) | 21,825 ± 3,835 | 8,297 ± 5,628 | -13,528 (-17,548; -9,508) | <0.001 |
Average midazolam consumption per day of MV (mg/day) | 329 ± 70 | 163 ± 115 | -167 (-246; -87) | <0.001 |
Monthly average propofol consumption (mg) | 36,210 ± 12,506 | 40,297 ± 10,459 | 4,088 (-5,422; 13,598) | 0.383 |
Average propofol consumption per day of MV (mg/day) | 541 ± 190 | 779 ± 210 | 238 (72; 404) | 0.007 |
Monthly average fentanyl consumption (μg) | 30,021 ± 9,029 | 19,057 ± 4,302 | -10,964 (-16,670; -5,258) | 0.001 |
Average fentanyl consumption per day of MV (μg/day) | 458 ± 170 | 370 ± 90 | -88 (-202; 25) | 0.120 |
Monthly average dexmedetomidine consumption (μg) | 4,350 ± 1,592 | 5,186 ± 2,066 | 836 (-700; 2,372) | 0.272 |
Average dexmedetomidine consumption per day of MV (μg/day) | 65 ± 20 | 100 ± 40 | 35 (07; 62) | 0.017 |
Monthly average haloperidol consumption (mg) | 176.4 ± 24 | 195.0 ± 61 | 18.7 (-20.0; 57.5) | 0.328 |
Average haloperidol consumption per day of MV (mg/day) | 03 ± 0.5 | 04 ± 1.0 | 1.1 (0.4; 1.7) | 0.002 |