Skip to main content

Advertisement

Table 4 Characteristics of the mechanically ventilated patients a

From: Evaluation of a minimal sedation protocol using ICU sedative consumption as a monitoring tool: a quality improvement multicenter project

  Preintervention (n= 2,446) Postintervention (n= 2,405) P-value
Characteristics October 2010 to September 2011 October 2011 to October 2012  
Age, yr, mean ± SD 62.37 ± 19 61.99 ± 18 0.467
Male, n (%) 1,306 (53.4) 1,275 (53.0) 0.792
BMI, kg/m2, mean ± SD 26.7 ± 6 26.7 ± 6 0.726
SAPS III score, mean ± SD 52.65 ± 19 51.44 ± 20 0.031
Charlson index score, median (IQR) 1 (0; 2) 1 (0; 2) 0.181
Admission type, n (%)    0.119
Medical 1,547 (63.2) 1,452 (60.4)  
Elective surgical 767 (31.4) 811 (33.7)  
Emergency surgical 132 (5.4) 142 (5.9)  
Diagnosis category, n (%)   
Cardiovascular 219 (9.0) 208 (8.6) 0.708
Sepsis 505 (20.6) 548 (22.8) 0.071
Neurological 284 (11.6) 276 (11.5) 0.883
Respiratoryb 303 (12.4) 182 (7.6) <0.001
Orthopedic surgery 28 (1.1) 31 (1.3) 0.647
Neurosurgery 63 (2.6) 47 (2.0) 0.146
Thoracic surgery 24 (1.0) 31 (1.3) 0.311
Cardiac surgery 545 (22.3) 627 (26.1) 0.002
Resources during ICU, n (%)   
RRT 174 (7.1) 185 (7.7) 0.441
Vasopressors 1,321 (54) 1,436 (59.7) <0.001
Noninvasive ventilation 639 (26.1) 612 (25.4) 0.590
Mechanical ventilation, n (%)   
During ICU stay 2,446 (100) 2,405 (100) -
At ICU admission 1,677 (68.6) 1,673 (69.6) 0.450
Tracheotomy 314 (12.8) 237 (9.9) 0.001
Length of mechanical ventilation   
Mean ± SD 3.91 ± 6.2 3.15 ± 4.6 <0.001
Median (IQR) 1 (1; 4) 1 (1; 3) 0.001
MV >24 hr 1,007 (41.1) 971 (40.2) 0.510
28 ventilator-free days    
Mean ± SD 16.07 ± 12.2 18.33 ± 11.6 <0.001
Median (IQR) 24 (0; 27) 26 (0; 27) <0.001
ICU LOS, days    
Mean ± SD 8.87 ± 11.9 7.46 ± 9.2 <0.001
Median (IQR) 5 (2; 12) 4 (2; 10) <0.001
Total hospital LOS, days    
Mean ± SD 23.75 ± 33.7 23.80 ± 31.3 0.961
Median (IQR) 13 (6; 28) 13 (6; 27) 0.707
Mortality, % (95% CI)    
ICU mortality 36.8% (35.0; 38.8) 29.6% (27.8; 31.4) <0.001
Hospital mortality 45.4% (43.5; 47.4) 38.1% (36.2; 40.1) <0.001
  1. aBMI, Body mass index; ICU, Intensive care unit; MV, Mechanical ventilation; RRT, Renal replacement therapy. bRespiratory diagnosis except pneumonia.