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Table 1 Patient's characteristics at Intensive Care Unit admission

From: Diagnosing external ventricular drain-related ventriculitis by means of local inflammatory response: soluble triggering receptor expressed on myeloid cells-1

Variable

All cases

Ventriculitis

Colonization only

Controls

P

(number = 73)

(number = 6)

(number = 10)

(number = 57)

Age

61 ± 12.2

59.3 ± 14.4

65 ± 11.5

60.46 ± 12.15

0.873

Male sex

37 (50.7)

2 (33.3)

5 (50)

30 (52.6)

0.667

Comorbidities

     

Hypertension

42 (57.5)

4 (66.7)

6 (60)

32 (56.1)

0.872

Diabetes mellitus

6 (8.2)

0 (0)

1 (10)

5 (8.8)

0.740

Dyslipidemia

25 (34.2)

3 (50)

3 (30)

19 (33.3)

0.683

Smoking

15 (20.5)

2 (33.3)

0 (0)

13 (22.8)

0.186

CIC

9 (12.3)

0 (0)

0 (0)

9 (15.8)

0.237

Previous CVA

13 (17.8)

2 (33.3)

2 (20)

9 (15.8)

0.554

CRI

2 (2.7)

0 (0)

0 (0)

2 (3.5)

0.749

Hepatopathy

2 (2.7)

0 (0)

0 (0)

2 (3.5)

0.749

Neoplasm

3 (4.1)

0 (0)

0 (0)

3 (5.3)

0.645

Immunodeficiency

2 (2.7)

1 (16.7)

0 (0)

1 (1.8)

0.088

APACHE II

20.3 ± 6.8

20.5 ± 6.7

19.3 ± 8±6

20.48 ± 6.58

0.675

Neurological pathology

    

0.051

SAH

31 (42.5)

3 (50)

5 (50)

23 (40.4)

 

ICH

34 (46.6)

3 (50)

2 (20)

29 (50.9)

Primary IVH

5 (6.8)

0 (0)

1 (10)

4 (7)

Acute ischemic stroke

2 (2.7)

0 (0)

2 (20)

0 (0)

Neoplasm

1 (1.4)

0 (0)

0 (0)

1 (1.8)

Secondary IVH

67 (92)

6 (100)

7 (70)

54 (94.7)

0.024

Type of EVD

    

0.022

Standard (PVC)

37 (50.7)

3 (50)

6 (60)

28 (49.1)

 

Antimicrobial impregnated

31 (42.5)

2 (33.3)

3 (30)

26 (45.6)

Silver-impregnated

1 (1.4)

1 (16.7)

0 (0)

0 (0)

Unknown

4 (5.5)

0 (0)

1 (10)

3 (5.3)

Prophylactic antibiotic therapy

48 (66)

5 (83)

9 (90)

34 (60)

0.112

EVD duration (days)

9.6 ± 5.3

14.8 ± 3.8

11.3 ± 4.9

8.8 ± 5.12

0.019

Other nosocomial infections

    

0.193

Tracheitis

8 (11)

1 (16.7)

1 (10)

6 (10.5)

VAP

16 (22)

3 (50)

5 (50)

8 (14)

CRB

2 (2.7)

0 (0)

0 (0)

2 (3.5)

UTI

2 (2.7)

0 (0)

1 (10)

1 (1.8)

ICU mortality

27 (37)

4 (66.7)

1 (10)

22 (38.6)

0.065

30-day mortality

32 (43.8)

4 (66.7)

5 (50)

23 (38.6)

0.426

  1. Data expressed as mean ± standard deviation or number (%), unless otherwise specified. APACHE II, Acute Physiology and Chronic Health Evaluation II: CIC, chronic ischemic cardiomyopathy; CRB, catheter related bacteremia; CRI, chronic renal insufficiency; CVA, cerebrovascular accident; EVD, external ventricular drainage; ICH, intracerebral hemorrhage; IVH, intraventricular hemorrhage; ICU, intensive care unit; PVC, polyvinyl chloride; SAH, subarachnoid hemorrhage; UTI, urinary tract infection; VAP, ventilator-associated pneumonia.
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