Table 1 Characteristics of 30-day survivor and non-survivor patients
Data | Survivors (n =311) | Non-survivors (n =73) | P -value |
|---|---|---|---|
Age, years, median (percentile 25 to 75) | 61 (50 to 71) | 71 (59 to 76) | 0.44 |
Sex, female, n (%) | 210 (67.5) | 43 (58.9) | 0.17 |
Admission diagnostic, n (%) | 0.15 | ||
Medical | 203 (65.3) | 56 (76.7) | |
Surgical | 81 (26.0) | 14 (19.2) | |
Traumatology | 27 (8.7) | 3 (4.1) | |
Diabetes mellitus, n (%) | 75 (24.1) | 22 (30.1) | 0.30 |
Chronic obstructive pulmonary disease, n (%) | 39 (12.5) | 17 (23.3) | 0.03 |
Corticosteroids, n (%) | 55 (17.7) | 17 (23.3) | 0.32 |
Antibiotics, n (%) | 225 (72.3) | 56 (76.7) | 0.56 |
Tracheostomy, n (%) | 54 (17.4) | 17 (23.3) | 0.24 |
Temperature, °C, median (percentile 25 to 75) | 38.0 (37.8 to 38.4) | 38.4 (38.0 to 38.5) | 0.44 |
Leukocytes, median*103/mm3 (percentile 25 to 75) | 10.6 (8.2 to 15.4) | 12.6 (8.5 to 19.5) | 0.01 |
Neutrophils, median*103/mm3 (percentile 25 to 75) | 8.2 (5.9 to 12.6) | 10.0 (6.8 to 14.8) | 0.18 |
Pa02/FI02 ratio, median (percentile 25 to 75) | 225 (177 to 294) | 190 (110 to 331) | 0.26 |
Platelets, median*103/mm3 (percentile 25 to 75) | 225 (116 to 317) | 187 (63 to 217) | 0.16 |
aPTT, seconds, median (percentile 25 to 75) | 29 (26 to 30) | 31 (27 to 34) | 0.61 |
International normalized ratio, median (percentile 25 to 75) | 1.1 (1.0 to 1.2) | 1.1 (1.0 to 1.1) | 0.86 |
SOFA score, median (percentile 25 to 75) | 5 (4 to 8) | 8 (5 to 13) | <0.001 |
Lactic acid, mmol/L, median (percentile 25 to 75) | 1.2 (0.9 to 1.6) | 1.7 (1.0 to 2.3) | <0.001 |
Bilirubin, mg/dl, median (percentile 25 to 75) | 0.6 (0.4 to 0.9) | 0.7 (0.3 to 2.3) | 0.40 |
Creatinine, mg/dl, median (percentile 25 to 75) | 0.8 (0.6 to 1.4) | 0.7 (0.5 to 1.0) | 0.57 |
CVC decision at moment of CRI suspicion, n (%) | 0.26 | ||
CVC removal without new catheter | 28 (9.0) | 6 (8.2) | |
CVC removal with new catheter | 140 (45.0) | 40 (54.8) | |
Watchful waiting without conservative cultures for diagnosis of CRBSI | 99 (31.8) | 15 (20.5) | |
Watchful waiting with conservative cultures for diagnosis of CRBSI | 44 (14.1) | 12 (16.4) | |
Moment of CVC removal, n (%) | 0.31 | ||
No CVC removal | 96 (30.9) | 20 (27.4) | |
CVC removal at moment of CRI suspicion | 168 (54.0) | 46 (63.0) | |
CVC removal later at moment of CRI suspicion | 47 (15.1) | 7 (9.6) | |
Cause of symptomatology, n (%) | 0.03 | ||
CRBSI | 45 (14.5) | 3 (4.1) | |
Pneumonia | 69 (22.2) | 32 (43.8) | |
Tracheobronchitis | 53 (17.0) | 7 (9.6) | |
Urinary infection | 22 (7.1) | 5 (6.8) | |
Skin infection | 15 (4.8) | 6 (8.2) | |
Osteomyelitis | 2 (0.6) | 0 | |
Central nervous system infection | 3 (1.0) | 1 (1.4) | |
Abdominal infection | 22 (7.1) | 5 (6.8) | |
Otitis | 1 (0.3) | 0 | |
Non-infectious | 5 (1.6) | 2 (2.7) | |
Unknown | 74 (23.8) | 12 (16.4) | |
CRBSI as cause of symptomatology, n (%) | 45 (14.5) | 3 (4.1) | 0.02 |