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Figure 2 | Critical Care

Figure 2

From: Alveolar pentraxin 3 as an early marker of microbiologically confirmed pneumonia: a threshold-finding prospective observational study

Figure 2

Pentraxin 3 as an early marker of pneumonia. Area under the receiver operating characteristic curve (AUCROC) analysis showed that Pentraxin 3 (PTX3) levels in bronchoalveolar lavage fluid (BALf) levels predicted pneumonia (AUCROC =0.815, 95% CI =0.710 to 0.921, P <0.0001), but that BALf levels of soluble triggering receptor expressed on myeloid cells 1 (s-TREM-1), plasma PTX3, C-reactive protein (CRP) and procalcitonin (PCT) levels did not. A cutoff of PTX3 levels ≥1 ng/ml in BAL fluid (identified by Youden index) was associated with 92% sensitivity, 60% specificity, 49% positive predictive value and 95% negative predictive value for culture-positive pneumonia.

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