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Table 3 Characteristics of patients requiring perioperative blood transfusion following scheduled abdominal surgery

From: Perioperative blood transfusion is associated with a gene transcription profile characteristic of immunosuppression: a prospective cohort study

 

Transfused, n =15 (13%)

Not transfused, n =103 (87%)

Pvalue

Age (years)

77 (72-81)

63 (56-70)

0.0002

Male sex (%)

60

62

1.0

Diabetes (%)

20

17

0.72

Current smokers (%)

0

23

0.04

Smoking history (%)

27

58

0.02

Cancer diagnosis (%)

93

60

0.02

Preoperative immunosuppression (%)

29

12

0.10

Duration of operation (minutes)

240 (150-400)

212 (145-296)

0.26

Endoscopic surgery (%)

13

29

0.35

Planned postoperative intensive care unit admission (%)

87

68

0.22

ASA grade 3 or 4 (%)

50

28

0.18

By surgical specialty n (%)

General surgery

0 (0)

8 (7)

 

Upper gastrointestinal

4 (27)

23 (22)

 

Colorectal

5 (33)

44 (43)

 

HPB

5 (33)

25 (24)

 

HPB + colorectal

1 (7)

2 (2)

 

General surgery + colorectal

0 (0)

1 (1)

0.65a

Postoperative infections n (%)

10 (66%)

34 (33%)

0.02

Inhospital death n (%)

2 (13%)

1 (1%)

0.04

  1. Data are described as medians with interquartile range or numbers with percentages in parenthesis. mRNA levels are expressed as a relative quantification ratio between the candidate and the reference genes. aRepresents a Fisher's exact test incorporating all surgical specialties. ASA, American Society of Anesthesiology; HPB, Hepato-Pancreato-Biliary.