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Table 2 Characteristics of patients developing infections and those remaining infection-free following scheduled abdominal surgery

From: Perioperative blood transfusion is associated with a gene transcription profile characteristic of immunosuppression: a prospective cohort study

 

Infection, n =44 (37%)

Infection-free, n =75 (63%)

Pvalue

Age (years)

66 (59-75)

64 (56-71)

0.19

Male sex (%)

61

63

>0.99

Diabetes (%)

18

16

0.80

Current smokers (%)

23

19

0.64

Smoking history (%)

48

57

0.34

Cancer diagnosis (%)

55

71

0.10

Preoperative immunosuppression (%)

14

14

>0.99

Duration of operation (minutes)

243 (176-313)

195 (142-295)

0.06

Endoscopic surgery (%)

18

32

0.13

Planned postoperative intensive care unit admission (%)

77

66

0.22

ASA grade 3 or 4 (%)

30

31

>0.99

By surgical specialty n (%)

General surgery

4 (44)

5 (55)

 

Upper gastrointestinal

9 (33)

18 (67)

 

Colorectal

18 (37)

31 (63)

 

HPB

11 (37)

19 (63)

 

HPB + colorectal

1 (33)

2 (67)

 

General surgery + colorectal

1 (100)

0 (0)

0.84a

Intraoperative blood transfusion (%)

14

5

0.17

Blood transfusion in the first 24 hours (%)

23

7

0.02

Inhospital death n (%)

1 (2%)

2 (2.5%)

>0.99

  1. Data are described as medians with interquartile range or numbers with percentages in parenthesis. mRNA levels are expressed as a relative quantification ratio between the candidate and the reference genes. aRepresents a Fisher's exact test incorporating all surgical specialties. ASA, American Society of Anesthesiology; HPB, Hepato-Pancreato-Biliary.