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Table 1 Lack of evidence of nosocomial infection in a retrospective cohort of patients dying of sepsis

From: Is nosocomial infection really the major cause of death in sepsis?

Age range (years)

Source of infection

SOFA score

ICU LOS (days)

Days from diagnosis to death

Days from final culture to death

Final culture result

Cause of death

Evidence of nosocomial infection

70 to 79

Lung

12

16

13

1

No growth

Cancer

No nosocomial infection

60 to 69

Skin and soft tissue

9

55

55

5

No growth

CHF

No nosocomial infection

80 to 89

Genitourinary

12

1

14

2

No growth

CHF

No nosocomial infection

70 to 79

Bloodstream

15

17

17

2

Original organism

IE/sepsis

No nosocomial infection

80 to 89

Lung

18

54

73

<1

Original organism

Ischemic bowel

No nosocomial infection

40 to 49

Intra-abdominal

12

14

14

14

No growth

Liver failure

No nosocomial infection

80 to 89

Lung

11

12

10

1

No growth

MI

No nosocomial infection

70 to 79

Lung

10

5

3

1

Original organism

MI

No nosocomial infection

40 to 49

Bloodstream

21

14

4

1

No growth

MOF

No nosocomial infection

50 to 59

Bloodstream

15

16

33

3

No growth

MOF

No nosocomial infection

40 to 49

Intra-abdominal

17

4

5

1

No growth

MOF

No nosocomial infection

70 to 79

Intra-abdominal

16

42

43

3

No growth

MOF

No nosocomial infection

60 to 69

Lung

9

19

18

2

No growth

MOF

No nosocomial infection

50 to 59

Skin and soft tissue

13

10

11

1

No growth

MOF

No nosocomial infection

60 to 69

Skin and soft tissue

14

76

57

2

No growth

MOF

No nosocomial infection

<30

Skin and soft tissue

14

86

85

<1

No growth

MOF

No nosocomial infection

80 to 89

Genitourinary

16

1

1

1

Original organism

MOF

No nosocomial infection

70 to 79

Lung

4

34

22

3

No growth

Tumor lysis

No nosocomial infection

40 to 49

Intra-abdominal

7

46

74

1

New organism

MOF

Nosocomial infection

70 to 79

Intra-abdominal

5

6

6

1

New organism

MOF

Nosocomial infection

<30

Intra-abdominal

12

37

37

<1

New organism

Pancreatitis

Nosocomial infection

60 to 69

Intra-abdominal

5

1

7

3

New organism

MOF

Indeterminate

50 to 59

Skin and soft tissue

12

37

37

4

No growth

MOF

Indeterminate

40 to 49

Lung

16

68

50

6

No growth

MOF

Indeterminate

70 to 79

Lung

13

17

17

13

Original organism

MOF

Indeterminate

70 to 79

Intra-abdominal

14

3

13

<1

No growth

Sepsis

Indeterminate

  1. The initial antibiotic therapy was checked against culture and sensitivity results to record the appropriateness of antibiotic therapy for the initial isolate. Results of the final culture before death and the time from that culture until death are indicated (<1 means the same day as death). CHF, congestive heart failure; IE, infective endocarditis; LOS, length of stay; MI, myocardial infarction; MOF, multiorgan failure; SOFA, Sequential Organ Failure Assessment.