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Table 1 Lack of evidence of nosocomial infection in a retrospective cohort of patients dying of sepsis

From: Is nosocomial infection really the major cause of death in sepsis?

Age range (years) Source of infection SOFA score ICU LOS (days) Days from diagnosis to death Days from final culture to death Final culture result Cause of death Evidence of nosocomial infection
70 to 79 Lung 12 16 13 1 No growth Cancer No nosocomial infection
60 to 69 Skin and soft tissue 9 55 55 5 No growth CHF No nosocomial infection
80 to 89 Genitourinary 12 1 14 2 No growth CHF No nosocomial infection
70 to 79 Bloodstream 15 17 17 2 Original organism IE/sepsis No nosocomial infection
80 to 89 Lung 18 54 73 <1 Original organism Ischemic bowel No nosocomial infection
40 to 49 Intra-abdominal 12 14 14 14 No growth Liver failure No nosocomial infection
80 to 89 Lung 11 12 10 1 No growth MI No nosocomial infection
70 to 79 Lung 10 5 3 1 Original organism MI No nosocomial infection
40 to 49 Bloodstream 21 14 4 1 No growth MOF No nosocomial infection
50 to 59 Bloodstream 15 16 33 3 No growth MOF No nosocomial infection
40 to 49 Intra-abdominal 17 4 5 1 No growth MOF No nosocomial infection
70 to 79 Intra-abdominal 16 42 43 3 No growth MOF No nosocomial infection
60 to 69 Lung 9 19 18 2 No growth MOF No nosocomial infection
50 to 59 Skin and soft tissue 13 10 11 1 No growth MOF No nosocomial infection
60 to 69 Skin and soft tissue 14 76 57 2 No growth MOF No nosocomial infection
<30 Skin and soft tissue 14 86 85 <1 No growth MOF No nosocomial infection
80 to 89 Genitourinary 16 1 1 1 Original organism MOF No nosocomial infection
70 to 79 Lung 4 34 22 3 No growth Tumor lysis No nosocomial infection
40 to 49 Intra-abdominal 7 46 74 1 New organism MOF Nosocomial infection
70 to 79 Intra-abdominal 5 6 6 1 New organism MOF Nosocomial infection
<30 Intra-abdominal 12 37 37 <1 New organism Pancreatitis Nosocomial infection
60 to 69 Intra-abdominal 5 1 7 3 New organism MOF Indeterminate
50 to 59 Skin and soft tissue 12 37 37 4 No growth MOF Indeterminate
40 to 49 Lung 16 68 50 6 No growth MOF Indeterminate
70 to 79 Lung 13 17 17 13 Original organism MOF Indeterminate
70 to 79 Intra-abdominal 14 3 13 <1 No growth Sepsis Indeterminate
  1. The initial antibiotic therapy was checked against culture and sensitivity results to record the appropriateness of antibiotic therapy for the initial isolate. Results of the final culture before death and the time from that culture until death are indicated (<1 means the same day as death). CHF, congestive heart failure; IE, infective endocarditis; LOS, length of stay; MI, myocardial infarction; MOF, multiorgan failure; SOFA, Sequential Organ Failure Assessment.