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Table 5 Comparison of post-ECPR care according to the neurologic outcome in the mECPR group (n = 52)

From: An optimal transition time to extracorporeal cardiopulmonary resuscitation for predicting good neurological outcome in patients with out-of-hospital cardiac arrest: a propensity-matched study

 

CPC 1, 2 (n = 8)

CPC 3 to 5 (n = 44)

P-value

ROSB after ECPR

8 (100)

34 (81.0)

0.328

MAP ≥60 mmHg within 2 hrs after ECPR, n (%)

8 (100)

25 (56.8)

0.021

Number of infused vasopressor/inotropics, n

2 (1 to 3)

2 (1 to 2)

0.945

Inotropic equivalent, μg/kg/min for 2 hrs post ECPR

32 (10 to 74)

59 (15 to 82)

0.180

LVEF after ECPR implantation

33 (18 to 48)

10 (0 to 20)

0.009

Therapeutic hypothermia, n (%)

5 (62.5)

9 (20.5)

0.025

 ROSB to target temperature (33°C), hrs

4 (2 to 6)

2.8 (1.6 to 3.0)

0.222 0.435

 Time on target temperature, hrs

24 (21 to 24)

24 (24 to 41)

 

CAG in patients with suspected ACS, n (%)

7 in 7 (100)

32 in 37 (86.5)

0.574

CAG findings

n =7

n = 32

0.015

No significant coronary lesion

2 (28.6)

3 (9.4)

 

 Coronary spasm, n (%)

0 (0)

3 (9.4)

 

 Coronary occlusion/stenosis, n (%)

5 (71.4)

26 (81.2)

 

 Diseased coronary artery, n (%)

n = 5

n = 26

0.719

 1 vessel

4 (80.0)

19 (73.1)

 

 2 vessels

1 (20.0)

4 (15.4)

 

 3 vessels

0 (0)

3 (11.5)

 

 PCI for coronary occlusion/stenosis

5 (100)

24 (92.3)

1.000

Complications during ECLS, n (%)

0 (0)

16 (36.4)

0.047

Bleeding at access site

-

12 (27.3)

 

Lower limb ischemia

-

3 (6.8)

 

Intracranial hemorrhage

-

1 (2.3)

 

Anterograde reperfusion catheter, n (%)

11 ( 25.0)

2 (25.0)

1.000

Amount of transfused pRBC

5 (3 to 12)

5 (1 to 10)

0.833

Successful weaning form ECLS, n (%)

8 (100)

2 (4.5)

<0.001

Duration of ECLS, hrs

43.6 (29.7 to 92.8)

17.9 (3.7 to 48.7)

0.026

  1. Data are shown as median (IQR) or number (%). CPR, cardiopulmonary resuscitation; ECPR, extracorporeal CPR; ROSB, return of spontaneous heart beat; LVEF, left ventricle ejection fraction; CAG, coronary angiography; ACS, acute coronary syndrome; PCI, percutaneous coronary intervention; ECLS, extracorporeal life support; pRBC, packed red blood cells.