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Table 3 Comparison of post-resuscitation care and outcomes between the mECPR and mCCPR groups

From: An optimal transition time to extracorporeal cardiopulmonary resuscitation for predicting good neurological outcome in patients with out-of-hospital cardiac arrest: a propensity-matched study

 

mECPR (n = 52)

mCCPR (n = 52)

P-value

Rate of ROSB/ROSC (≥20 minutes), n (%)

42 (80.8)

20 (38.5)

< 0.001

Therapeutic hypothermia, n (%)

14 (26.9)

12 (23.1)

0.821

CAG in patients with suspected ACS (%)

39 in 44 (88.6)

11 in 15 (73.3)*

0.213

CAG findings

n = 39

n = 11

0.010

 No significant coronary lesion

5 (12.8)

4 (36.4)

 

 Coronary spasm

3 (7.7)

4 (36.4)

 

 Presence of coronary occlusion/stenosis, n (%)

31 (79.5)

3 (27.3)

 

 Diseased coronary artery, n (%)

n = 31

n = 3

0.603

 1 vessel

23 (74.2)

3 (100)

 

 2 vessels

5 (16.1)

0 (0)

 

 3 vessels

3 (9.7)

0 (0)

 

 PCI for coronary occlusion/stenosis

29 (93.5)

3 (100)

1.000

CPC score at discharge

  

0.011

 1, n (%)

7 (13.5)

1 (1.9)

 

 2, n (%)

1 (1.9)

0

 

 3, n (%)

0

2 (3.8)

 

 4, n (%)

1 (1.9)

8 (15.4)

 

 5, n (%)

43 (82.7)

41 (78.8)

 

Hospital LOS in survival to discharge, days

30 (14 to 60)

28 (16 to 50)

0.766

CPC score at 3 months post arrest

  

0.070

 1, n (%)

7 (13.5)

1 (1.9)

 

 2, n (%)

1 (1.9)

0 (0)

 

 3, n (%)

0 (0)

2 (3.8)

 

 4, n (%)

0 (0)

1 (1.9)

 

 5, n (%)

44 (84.6)

48 (92.3)

 

Final diagnosis of arrest, n (%)

  

< 0.001

 Cardiac

   

 ACS/AMI

36 (69.2)

9 (17.3)

 

 Lethal arrhythmia

3 (5.8)

5 (9.6)

 

 HF, HCMP, DCMP

3 (5.8)

2 (3.8)

 

 Pulmonary embolism

2 (3.8)

1 (1.9)

 

 Unknown sudden arrest

4 (7.7)

31 (59.6)

 

 Non-cardiac

   

 Respiratory arrest

1 (1.9)

0 (0)

 

 Hypothermia

1 (1.9)

0 (0)

 

 Acute kidney injury

1 (1.9)

3 (5.8)

 

 Brain hemorrhage

1 (1.9)

1 (1.9)

 

Causes of death at 3 months post arrest, n (%)

n = 44

n = 48

< 0.001

 No ROSB or ROSC

10 (22.7)

32 (66.7)

 

 Refractory shock

24 (54.5)

4 (8.4)

 

 Hypoxic brain injury and organ failure

8 (18.2)

12 (25.0)

 

 Brain death

2 (4.5)

0 (0)

 
  1. Data are shown as median (IQR) or number (%). *In 15 suspected ACS patients with ROSC (≥20 minutes). CPR, cardiopulmonary resuscitation; ECPR, extracorporeal CPR; CCPR, conventional CPR; ROSB, return of spontaneous heart beat; ROSC, return of spontaneous circulation; CAG, coronary angiography; ACS, acute coronary syndrome; PCI, percutaneous coronary intervention; CPC, cerebral performance category; LOS, length of stay; HF, heart failure; HCMP, hypertrophic cardiomyopathy; DCMP, dilated cardiomyopathy.