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Table 5 Multivariate logistic regression analysis of independent risk factors for 28-day mortality

From: Early versus delayed administration of norepinephrine in patients with septic shock

Variable Adjusted Odds Ratio of Death 95% Confidence interval Pvalue
Risk factors    
Time to initial norepinephrine administration (h) 1.392 1.138-1.702 0.003
Time to initial antimicrobial treatment (h) 1.330 1.067-1.659 0.011
Serum lactate at septic shock onset (mmol/L) 1.710 1.174-2.537 0.005
APACHE II score 1.243 1.096-1.409 <0.001
Protective factors    
Effective antimicrobial therapy 0.477 0.231-0.982 0.040
Volume of intravenous fluids within 6 h (L) 0.676 0.468-0.977 0.033
  1. Hosmer-Lemeshow goodness-of-fit test, P =0.627.