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Table 5 Multivariate logistic regression analysis of independent risk factors for 28-day mortality

From: Early versus delayed administration of norepinephrine in patients with septic shock

Variable

Adjusted Odds Ratio of Death

95% Confidence interval

Pvalue

Risk factors

   

Time to initial norepinephrine administration (h)

1.392

1.138-1.702

0.003

Time to initial antimicrobial treatment (h)

1.330

1.067-1.659

0.011

Serum lactate at septic shock onset (mmol/L)

1.710

1.174-2.537

0.005

APACHE II score

1.243

1.096-1.409

<0.001

Protective factors

   

Effective antimicrobial therapy

0.477

0.231-0.982

0.040

Volume of intravenous fluids within 6 h (L)

0.676

0.468-0.977

0.033

  1. Hosmer-Lemeshow goodness-of-fit test, P =0.627.