From: Early versus delayed administration of norepinephrine in patients with septic shock
Variable | Adjusted Odds Ratio of Death | 95% Confidence interval | Pvalue |
---|---|---|---|
Risk factors | |||
Time to initial norepinephrine administration (h) | 1.392 | 1.138-1.702 | 0.003 |
Time to initial antimicrobial treatment (h) | 1.330 | 1.067-1.659 | 0.011 |
Serum lactate at septic shock onset (mmol/L) | 1.710 | 1.174-2.537 | 0.005 |
APACHE II score | 1.243 | 1.096-1.409 | <0.001 |
Protective factors | |||
Effective antimicrobial therapy | 0.477 | 0.231-0.982 | 0.040 |
Volume of intravenous fluids within 6 h (L) | 0.676 | 0.468-0.977 | 0.033 |