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Figure 7 | Critical Care

Figure 7

From: Endothelial dysfunction and renal fibrosis in endotoxemia-induced oliguric kidney injury: possible role of LPS-binding protein

Figure 7

Inhibition of EC dysfunction by CPFA treatment. (A) In endotoxemic animals, the reduced CD31 (red) expression at vascular level (dotted white arrow) was reversed after 6 hours of CPFA treatment (dotted white arrow). The increased number of CD31+/α-SMA+ cells induced by LPS infusion (white arrows) was significantly hampered in treated pigs (white arrows). (B) Results are expressed as median ± IQR of the numbers of CD31+/α-SMA+ cells/HPF of at least five independent animals for each group. (C) Comparison of zoomed peritubular capillaries of endotoxemic (white arrow) and treated endotoxemic pigs (white arrow). Magnification, 630×. To-pro 3 was used to counterstain nuclei (blue).

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