| Number of studies included | Effect size (95%CI) | Homogeneity index, Q | Between-study variability, I 2 |
---|---|---|---|---|
Type of patient | Â | Â | ||
All ICU | 1.513 (1.123 to 2.039) | 39.822, P <0.01 | 84.933 | |
Sepsis and shock | 0.831 (0.203 to 3.413) | 8.041, P = 0.005 | 87.563 | |
Surgical | 1.174 (0.682 to 2.023) | 6.793, P = 0.033 | 70.556 | |
Trauma | 2.705 (0.815 to 8.973) | 30.695, P <0.01 | 93.484 | |
Other | 0.940 (0.417 to 2.116) | 15.505, P <0.01 | 87.101 | |
Outcome measurement | Â | Â | ||
Count data | 3.969 (2.023 to 7.788) | 28.936, P <0.01 | 96.544 | |
OR | 1.465 (1.049 to 2.045) | 30.191, P <0.01 | 70.190 | |
RR and HR | 0.901 (0.622 to 1.305) | 31.039, P <0.01 | 91.391 | |
Adjustment | Â | Â | Â | |
Unadjusted | 3.933 (2.107 to 7.343) | 28.936, P <0.01 | 96.544 | |
No propensity matched but multiple adjusted | 1.358 (0.965 to 1.910) | 25.626, P <0.01 | 68.782 | |
Propensity score matched | 1.089 (0.767 to 1.546) | 60.523, P <0.01 | 90.086 | |
Leukoreduced usage | Â | Â | Â | |
Not reported | 1.851 (1.229 to 2.786) | 86.863, P <0.01 | 88.488 | |
<50% | 1.155 (0.583 to 2.290) | 52.156, P <0.01 | 96.165 | |
~76% | 0.966 (0.412 to 2.267) | 14.812, P <0.01 | 93.249 | |
~100% | 1.031 (0.452 to 2.352) | 1.261, P = 0.26 | 20.696 |